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Sofosbuvir)
Sofosbuvir被合理地容忍了:不良事件是常见的(81%),但严重的不良事件(17%)和治疗不连续性(8%)是不常见的。
Sofosbuvir was reasonably well tolerated: adverse events were common(81%), but serious adverse events(17%) and treatment discontinuations(8%) were uncommon.年4月7日,美国食品和药物管理局批准了Sovaldi(sofosbuvir)和Harvoni(ledipasvir和sofosbuvir)在12至17岁儿童中治疗丙型肝炎病毒(HCV)的补充申请。
The US Food and Drug Administration on April 7 approved supplemental applications for sofosbuvir and ledipasvir and sofosbuvir(Harvoni) to treat HCV in children ages 12 to 17.Sofosbuvir是一种针对丙肝病毒的有效的直接抗病毒药物治疗,但是对潜在的肾脏毒性的担忧已经增加,尤其是在CKD患者身上。
Sofosbuvir is a potent direct-acting antiviral therapy against HCV, but concerns about potential kidney toxicity have been raised, particularly in patients with CKD.而为期12周的索华迪(Sofosbuvir)治疗,就是未涵盖在基本保险内的医治丙型肝炎的方案之一,费用为69,600元人民币(约9,700美元)。
A 12-week Sofosbuvir course, one of the treatments not covered by primary insurance, costs 69,600 yuan($ 9700 USD.MyHep所有药物都是sofosbuvir和velpatasvir的组合。
MyHep All is a medicine that is a mixture of Sofosbuvir& Velpatasvir.以下是含有Sofosbuvir的药物可能出现的副作用列表.
Below is a list of possible side effects that may occur in medications containing Sofosbuvir.例如,常见的对sofosbuvir耐药的变异是L159F,V321A,和S282R。
For example, common resistance-associated variants for sofosbuvir are L159F, V321A, and S282R.那名渔民的医生建议他服用包括索非布韦(sofosbuvir)之内的药物治疗。
The fisherman's doctor recommended treatment that included a drug called sofosbuvir.ASTRAL-3临床试验报道,基因3型患者予sofosbuvir+velpatasvir联合治疗12周后,SVR12为95%[57]。
The ASTRAL-3 trial reported an SVR 12 of 95% in genotype 3 patients treated with sofosbuvir+ velpatasvir for 12 weeks[57.在中等收入国家,用索非布韦(sofosbuvir)和达卡他韦(daclatasvir)治疗三个月的价格差别很大。
Among middle-income countries, the price for a three-month treatment of sofosbuvir and daclatasvir varies greatly.Simeprevir和sofosbuvir的组合的EC市场授权在处理naïve患者也包含从第2阶段研究,波斯菊的结果。
The EC marketing authorisation for the combination of simeprevir and sofosbuvir also contains results from the Phase 2 study, COSMOS, in treatment-naïve patients.包括索非布韦(sofosbuvir)和达卡他韦(daclatasvir)在内的所有5种产品已被纳入到清单之内。
All five products, including sofosbuvir and daclatasvir, were included in the List.Ledipasvir是一种HCVNS5A抑制剂和sofosbuvir是一种HCVNS5B聚合酶的核苷酸类似物抑制剂。
Ledipasvir is an HCV NS5A inhibitor and sofosbuvir is a nucleotide analog inhibitor of HCV NS5B polymerase.所有参与者每日服用一次联合使用ledipasvir(90毫克)和sofosbuvir(400毫克)两到六个月的药丸。
All participants will take a daily pill of combination ledipasvir(90 milligrams) and sofusbuvir(400 milligrams) for two to six months.Vosevi是一种固定剂量的组合片,含有两种已获批药物,Sofosbuvir(索非布韦),Velpatasvir(维帕他韦)和另一种新的药物Voxilaprevir。
Vosevi is a fixed-dose, combination tablet containing two previously approved drugs- sofosbuvir and velpatasvir- and a new drug, voxilaprevir.新疗法用到的主要药物是由吉利德制药公司(Gilead)生产的索非布韦(Sofosbuvir),通常会将它与另一种药物联合使用,以达到更好的疗效。
In the new regime, the main drug is Sofosbuvir(produced by Gilead) which is often combined with another drug to make it more effective.而为期12周的索华迪(Sofosbuvir)治疗,就是未涵盖在基本保险内的医治丙型肝炎的方案之一,费用为69,600元人民币(约9,700美元)。
A 12-week course of Sofosbuvir, one of the treatments not covered by basic insurance, costs 69,600 yuan($9700 USD.
Sofosbuvir is pregnancy category B.不建议HARVONI与其他含sofosbuvir(SOVALDI®)产品使用。
Patients should not take Harvoni with other products that contain sofosbuvir(e.g. Sovaldi.以下是含有Sofosbuvir的药物可能出现的副作用列表.
The following is a list of possible side-effects that may occur in medicines that contain Sofosbuvir.
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