PALIPERIDON in English translation

• paliperidone

Examples of using Paliperidon in Danish and their translations into English

kan have lignende effekt på paliperidon.
may have similar effects on paliperidone.

Det aktive stof, paliperidon, opløses, når tabletten kommer ned i maven,
The active ingredient, paliperidone, dissolves once swallowed and the tablet shell

Ved administration af INVEGA én gang dagligt opnås steady state- koncentration af paliperidon hos de fleste mennesker efter 4- 5 dage.
With once-daily dosing of INVEGA, steady-state concentrations of paliperidone are attained within 4-5 days of dosing in most subjects.

INVEGAS potentielle indvirkning på andre lægemidler Paliperidon forventes ikke at forårsage klinisk vigtige farmakokinetiske interaktioner med lægemidler, som metaboliseres af cytokrom P450- isozymer.
Potential for INVEGA to affect other medicines Paliperidone is not expected to cause clinically important pharmacokinetic interactions with medicines that are metabolised by cytochrome P-450 isozymes.

var plasmakoncentrationerne af frit paliperidon de samme som hos raske forsøgsdeltagere.
the plasma concentrations of free paliperidone were similar to those of healthy subjects.

Der bør udvises forsigtighed hvis paliperidon administreres samtidig med lægemidler der vides at sænke krampetærsklen f. eks. phenothiazin
Caution is advised if paliperidone is combined with other medicines know to lower the seizure threshold i. e. phenothiazines

herunder paliperidon.
including paliperidone.

kan medføre nedsat absorption af paliperidon.
may result in a reduced absorption of paliperidone.

Selv om der ikke er rapporteret tilfælde af priapisme i kliniske forsøg med INVEGA, har paliperidon samme farmakologiske aktivitet
Although no cases of priapism have been reported in clinical trials with INVEGA, paliperidone shares this pharmacologic activity

Et mindre fald i mængden af uforandret paliperidon udskilt i urinen tyder på, at der var lille effekt på CYP- metabolismen eller biotilgængeligheden af paliperidon, når det blev administreret sammen med carbamazepin.
A minor decrease in the amount of active substance excreted unchanged in the urine suggests that there was little effect on the CYP metabolism or bioavailability of paliperidone during carbamazepine co-administration.

Administration af paliperidon depottabletter sammen med et standardmåltid med højt indhold af fedt og kalorier øger paliperidons Cmax
Administration of paliperidone prolonged-release tablets with a standard high-fat/ high-caloric meal increases Cmax and AUC of paliperidone by up

In vitro- forsøg med humane levermikrosomer har vist, at paliperidon ikke væsentligt hæmmer metaboliseringen af lægemidler, som metaboliseres af cytokrom P450- isozymer,
In vitro studies in human liver microsomes showed that paliperidone does not substantially inhibit the metabolism of medicines metabolised by cytochrome P450 isozymes,

Da paliperidon er et stof, der er fremkommet ved nedbrydning af risperidon(anden medicin, som bruges til behandling af skizofreni)
Since paliperidone is a compound resulting from the breakdown of risperidone(another medicine used to treat schizophrenia)

disse isozymer spiller en signifikant rolle i metaboliseringen af paliperidon.
in vivo that these isozymes play a significant role in the metabolism of paliperidone.

CYP3A4 spiller en rolle i metaboliseringen af paliperidon, findes der ingen in vivo- evidens for, at disse isozymer spiller en signifikant rolle i metaboliseringen af paliperidon..
role for CYP2D6 and CYP3A4 in the metabolism of paliperidone, there is no evidence in vivo that these isozymes play a significant role in the metabolism of paliperidone..

Xeplion(paliperidon) kom på markedet 2. maj 2011.
Xeplion(paliperidone palmitate) was marketed on May 2nd, 2011.

Invega(paliperidon) depottabletter er godkendt til behandling af skizofreni.
Invega(paliperidone) prolonged-release tablets are approved in treatment of schizophrenia.

Effekt og bivirkningsprofil svarer til dette stof, men paliperidon er ikke sammenlignet med risperidon i kliniske studier.
The effect and side effect profile correspond to that substance, but paliperidone has not been compared with risperidone in clinical studies.

Konklusion Paliperidon er den aktive metabolit af det atypiske antipsykotikum risperidon,
Paliperidone is the active metabolite of the atypical antipsychotic risperidone,

Xeplion(paliperidon palmitat), godkendt som depotinjektion(i. m) ved skizofreni til brug én gang månedligt.
Xeplion(paliperidone palmitate), has been approved as an extended-release injection(i.m.) for the treatment of schizophrenia.