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Nastanek majhnih količin konjugatov glutationa ni popolnoma izključen.
The formation of small amounts of glutathione conjugates cannot be completely excluded.10% vitanolid glikozid konjugatov.
10% withanolide glycoside conjugates.Zasledili pa so manjše količine presnovkov II. faze, in sicer glukuroniranih in sulfatiranih konjugatov.
Following administration of 14C-entecavir, no oxidative or acetylated metabolites and minor amounts of the phase II metabolites, glucuronide and sulfate conjugates, were observed.Stopnja vezave obetiholne kisline in njenih konjugatov v humani plazmi je večja kot 99.
Human plasma protein binding of obeticholic acid and its conjugates is greater than 99.Med pretvorbo konjugatov GSH(growth stimulating factor)
During conversion of GSH conjugates to N-acetylcysteine 10% vitanolid glikozid konjugatov.
10% withanolide glycoside conjugates.Konjugatov faze II oseltamivirja ali njegovih presnovkov in vivo niso odkrili.
No phase 2 conjugates of either compound have been identified in vivo.Poleg tega MMAD se poroča, da se uporablja pri izdelavi konjugatov protitelesnih zdravil, specifičnih za posamezne lokacije(NDC.
Additionally, MMAD is reported to be used in the production of site-specific antibody drug conjugates(NDCs.Od presnovkov v obtoku je večina glukuronidnih konjugatov posakonazola, opazili pa so le majhne količine oksidativnih presnovkov(presnova posredovana s CYP450.
Of the circulating metabolites, the majority are glucuronide conjugates of posaconazole with only minor amounts of oxidative(CYP450 mediated) metabolites observed.so manjše količine presnovkov II. faze, in sicer glukuroniranih in sulfatiranih konjugatov.
glucuronide and sulfate conjugates, were observed.Ravni konjugatov rotigotina in njegovih presnovkov po dealkilaciji v plazmi se pri okvarjenem delovanju ledvic povečajo, vendar ni vpliva teh presnovkov na klinične učinke.
Plasma levels of conjugates V vzorcih človeškega blata niso odkrili sulfatnih ali glukuronidnih konjugatov, kar kaže na to, da sulfatacija
Sulfate or glucuronide conjugates were not detected in the human faecal samples,15% znižanje očistka konjugatov raloksifena.
a 15% decrease in the clearance of raloxifene conjugates.15% znižanje o istka konjugatov raloksifena.
a 15% decrease in the clearance of raloxifene conjugates.Vendar je bila koncentracija sulfatnih konjugatov hidroksiaripiprazola v človeškem žolču v 39- tedenski raziskavi ob največjem priporočenem odmerku 30 mg na dan le 6% koncentracije v žolču pri opicah
However, the concentrations of the sulphate conjugates of hydroxy aripiprazole in human bile at the highest dose proposed, 30 mg per day, were no more than 6%odpornosti tumorjev, odziva na poškodbo DNK ter konjugatov protitelesa z zdravilom- in zagovarjanjem razvoja kombinacij po meri posameznika ima družba AstraZeneca vizijo,
DNA Damage Response and Antibody Drug Conjugates-- and by championing the development of personalized combinations, AstraZeneca has theintramolekulska prerazporeditev cisteinilglicinskih in cisteinskih konjugatov s poznejšo dimerizacijo.
intramolecular rearrangement of the cysteinylglycine and cysteine conjugates with subsequent dimerisation.C po Child-Pughovi lestvici) povprečna vrednost AUC skupne obetiholne kisline in njenih dveh aktivnih konjugatov povečala za faktor 1,13(razred A),
mean AUC of total obeticholic acid, the sum of obeticholic acid and its two active conjugates, increased by 1.13-, 4-To je zato, ker ima tako kot konjugatov, kar pomeni, da prav jim je, kot konjugatov,
This is because has both as conjugates, which means that also has them as Testosteron se izloča v glavnem z urinom v obliki konjugatov glukuronske in žveplove kisline testosterona ter njegovih presnovkov.
Testosterone is mainly excreted in the urine as glucuronic and sulphuric acid conjugates of testosterone and its metabolites.
