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bo družba, ki ga trži, zagotovila rezultate dveh študij, v katerih primerjajo učinke zdravila Darzalex, kadar se uporabi v kombinaciji z dvema drugima zdraviloma proti raku(tj. lenalidomidom in deksametazonom oziroma bortezomibom in deksametazonom),
the company that markets Darzalex will provide the results of two studies comparing the effect of Darzalex used in combination with other cancer treatments(i.e. lenalidomide and dexamethasone, or bortezomib so o globoki venski trombozi poročali pri 7,2% bolnikov, ki so se zdravili z zdravilom Empliciti v kombinaciji z lenalidomidom in deksametazonom(N= 318), in 3,8% bolnikov, ki so se zdravili z lenalidomidom in deksametazonom(N= 317.
with multiple myeloma(Study 1), deep vein thromboses were reported in 7.2% of patients treated with Empliciti combined with lenalidomide and dexamethasone(N= 318) 321 bolnikov na zdravljenje z zdravilom Empliciti v kombinaciji z lenalidomidom in deksametazonom, 325 bolnikov pa na zdravljenje z lenalidomidom in deksametazonom.
randomised to receive treatment: 321 to Empliciti in combination with lenalidomide and dexamethasone v katerih so primerjali zdravljenje z lenalidomidom in deksametazonom v primerjavi z zdravljenjem samo z deksametazonom pri bolnikih z diseminiranim plazmocitomom, ki so se že zdravili.
parallel-group controlled studies(MM-009 and MM-010) of lenalidomide plus dexamethasone therapy versus bolniki, ki so prejemali zdravilo Kyprolis skupaj z lenalidomidom in deksametazonom so povprečno živeli 26,3 meseca brez poslabšanja bolezni,
got worse again(progression-free survival): patients receiving Kyprolis plus lenalidomide and dexamethasone lived for an average of 26.3 months without their disease getting worse,izvedenem pri bolnikih z multiplim mielomom, v katerem so zdravljenje z zdravilom Empliciti v kombinaciji z lenalidomidom in deksametazonom(N= 318) primerjali z zdravljenjem z lenalidomidom in deksametazonom(N= 317), so prikazani v tabeli 4.
a clinical trial in patients with multiple myeloma comparing Empliciti combined with lenalidomide and dexamethasone treatment(N= 318) to lenalidomide and dexamethasone treatment(N= 317), is shown in Table 4.V kliničnem preskušanju, v katerem so pri bolnikih z multiplim mielomom uporabo zdravila Empliciti v kombinaciji z lenalidomidom in deksametazonom primerjali z uporabo lenalidomida
In a clinical trial of patients with multiple myeloma that compared Empliciti combined with lenalidomide and dexamethasone treatment to so se zdravili z zdravilom Empliciti v kombinaciji z lenalidomidom in deksametazonom daljša kot pri bolniki, ki so se zdravili z lenalidomidom in deksametazonom.
which was extended in patients treated with Empliciti combined with lenalidomide and dexamethasone vs. je vključevala bortezomib, ali napredovanje v prvih 3 mesecih po začetku zdravljenja z lenalidomidom in deksametazonom, ali napredovanje kadar koli med zdravljenjem z lenalidomidom in deksametazonom, če je le-to predstavljalo zadnjo uporabljeno linijo zdravljenja za preiskovanca.
disease progression during the treatment with a bortezomib-containing regimen, or progression during the first 3 months of initiating treatment with lenalidomide and dexamethasone, or progression at any time during treatment with lenalidomide and dexamethasone if this was the subject's most recent line of therapy.Odmerjanje pri uporabi z lenalidomidom in deksametazonom.
Posology for administration with lenalidomide and dexamethasone.Zdravilo Kyprolis v kombinaciji z lenalidomidom in deksametazonom.
Kyprolis in combination with lenalidomide and dexamethasone.Zdravilo uporabljamo v kombinaciji z lenalidomidom in deksametazonom.
It is used in combination with lenalidomide and dexamethasone.Kombinirana uporaba z lenalidomidom in deksametazonom ni vplivala na zavrtje proteasomov.
Combination dosing with lenalidomide and dexamethasone did not affect proteasome inhibition.Tabela 1: Priporočena shema odmerjanja zdravila Empliciti v kombinaciji z lenalidomidom in deksametazonom.
Table 1: Recommended dosing schedule of Empliciti in combination with lenalidomide and dexamethasone.Bolniki smejo nadaljevati z zdravljenjem z lenalidomidom in deksametazonom do napredovanja bolezni ali intolerance.
Patients may continue lenalidomide and dexamethasone therapy until disease progression or intolerance.Zdravilo Kyprolis boste dobili ali skupaj z lenalidomidom in deksametazonom ali skupaj s samim deksametazonom. .
Kyprolis will be given to you together with lenalidomide and dexamethasone, or only with Zdravilo Kyprolis v kombinaciji z lenalidomidom in deksametazonom za zdravljenje bolnikov z recidivnim diseminiranim plazmocitomom- študija PX-171-009(ASPIRE.
Kyprolis in combination with lenalidomide and dexamethasone for the treatment of patients with relapsed multiple myeloma- study PX-171-009(ASPIRE.Pri enem bolniku so poročali o prevelikem odmerjanju elotuzumaba v odmerku 23,3 mg/kg v kombinaciji z lenalidomidom in deksametazonom.
One patient was reported to be overdosed with 23.3 mg/kg of elotuzumab in combination with lenalidomide and dexamethasone.Ključni podatki za indikacijo uporabe zdravila Empliciti v kombinaciji z lenalidomidom in deksametazonom so bili pridobljeni v študiji 1.
Study 1 provided the pivotal data for the indication for Empliciti in combination with lenalidomide and dexamethasone.v kombinaciji z lenalidomidom in deksametazonom.
long in combination with lenalidomide and dexamethasone.
