Примери за използване на Molecular response на Английски и техните преводи на Български
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haematological, and molecular responses.
Skeletal muscle repair is a highly synchronized process involving both cellular and molecular responses, where the coordination between inflammation
Molecular response**.
Treatment discontinuation in CML patients in chronic phase who have achieved a sustained deep molecular response on nilotinib treatment following prior imatinib therapy.
Philadelphia chromosome positive CML patients in chronic phase who have achieved a sustained deep molecular response(MR 4.5) on Tasigna following prior imatinib therapy.
entered the TFR phase after achieving a sustained deep molecular response during the consolidation phase, defined by the following criterion.
haematological response, molecular response(evaluation of minimal residual disease),
C Major molecular response(at any time) was defined as BCR ABL ratios≤ 0.1% by RQ PCR in peripheral blood samples standardised on the International scale.
Loss of major molecular response(MMR=BCR-ABL/ABL≤0.1%IS) will trigger treatment re-initiation within 4 weeks of when loss of remission is known to have occurred.
achieved early molecular response(defined as BCR-ABL levels≤ 10% at 3 months) compared with imatinib-treated patients(64%).
Patients achieving early molecular response had a lower risk of transformation,
The rate of major molecular response(defined as BCR-ABL/ control transcripts≤ 0.1% by RQ-PCR in peripheral blood samples) prior to crossover was 29% for dasatinib and 12% for imatinib.
The rate of major molecular response(defined as BCR-ABL/control transcripts≤ 0.1% by RQ-PCR in peripheral blood samples) prior to crossover was 29% for dasatinib
Patients who re-initiate nilotinib therapy should have their BCR-ABL transcript levels monitored monthly until previous major molecular response or MR4 level is re-established and every 12 weeks thereafter(see section 4.4).
of patients treated with Bosulif had a major molecular response, compared with 37%(89 out of 241)
the major molecular response(MMR; BCR-ABL/ABL≤0.1% IS)
Patients with BCR-ABL levels≤10% at 3 months of treatment show a greater overall survival at 72 months compared to those who did not achieve this molecular response level(94.5% vs. 77.1% respectively[p=0.0005]).
The main measure of effectiveness was the number of patients who had a‘major molecular response'(where the amount in the bone marrow of BCR-ABL,
Monitoring of BCR-ABL transcript levels must be performed with a quantitative diagnostic test validated to measure molecular response levels on the International Scale(IS)
entered the TFR phase after achieving a sustained deep molecular response during the consolidation phase, defined by the following criterion:-