Glucosamine sulfate, MSM, and pine bark or grape seed extracts take some time to work, usually 2-4 weeks, but do not forego their use as they still are very important in supporting the manufacture of cartilage and other joint structures.
Bone Strength- the combination of grape seed extract and calcium may have a beneficial effect on bone formation, according to a 2005 study conducted on rats. This was an animal study, so human clinical trials are needed to confirm results.
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