A nuclear localisation signal(NLS) is also characterised, mutation of which leads to cytoplasmic localisation of Cdc25A.
目前还不清楚是什么原因导致DNA突变导致急性淋巴细胞白血病。
It's not clear what causes the DNA mutations that can lead to acute lymphocytic leukemia.
这种类型的多发性神经纤维瘤是极为罕见和发展的两个染色体的基因突变导致,即,染色体12和22.
This type of neurofibromatosis is extremely rare and it develops due to mutation of genes on both the chromosomes, i.e. chromosome 12 and 22.
在这项研究中,研究人员创造了携带相同基因突变导致疾病的果蝇。
For this study, researchers created fruit flies carrying the same genetic mutation that causes the disease.
如果DNA修复不正确,那么可能导致细胞产生一个灾难性的后果,其中之一就是增加突变导致癌症。
If DNA isn't repaired correctly, then that can result in disastrous consequences for cells, one of them being increased mutation that can lead to cancer.
有些人,主要是北欧,都继承MCM6该基因突变导致消化乳糖进入成年的能力,持久性。
Some people, primarily northern Europeans, have an inherited MCM6 gene mutation that leads to persistence in the ability to digest lactose into adulthood.
Impaired GABAA receptor function caused by mutations… thus(could) result in complex neurodevelopmental disorders including epilepsy, autism and intellectual disability,” they wrote.
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