Since the downstream genes of NF-kB include CyclinD1 and c-Myc, sustained activation of NF-kB stimulates cell growth, leading to uncontrolled cell proliferation.
为了使细胞增殖,必须有大量的天冬氨酸来产生新的细胞的RNA和DNA以及蛋白质。
For proliferating cells, there must be plenty of aspartate present to create all of the new cell's RNA and DNA, as well as its proteins.
Ki-67被认为涉及细胞增殖的维持,然而其发挥功能的机制尚未清楚。
Ki-67 is thought to be involved in the maintaining of cell proliferation, however, its exact mechanism for function is unknown.
细胞增殖和通过细胞凋亡而死亡的过程要更为复杂,其中涉及许多基因的参与。
The processes of cell proliferation and death by apoptosis are even more complex and involve the participation of many genes.
此外,ZM336372治疗显著抑制细胞增殖,并诱导细胞周期抑制剂p21和p18。
Furthermore, treatment with ZM336372 led to a marked suppression of cellular proliferation and induction of the cell cycle inhibitors p21 and p18.
令人惊喜的是,他们的技术不仅让祖细胞增殖,还促使它们生成新的、能让听力恢复的关键细胞毛细胞。
Surprisingly, their technique not only caused the progenitor cells to proliferate but also induced them to generate new hair cells- the key to restoring hearing.
我们必须记住,维持肌肉细胞增殖的反应器需要大量的能量:培养温度应在37-38℃。
We have to keep in mind that maintaining a reactor where muscle cells multiply requires a lot of energy: the culture should be at 37-38ºC.
这些角色共同使RET成为控制细胞增殖、存活和死亡的关键角色。
Together, these roles make RET a key player in the control of cell proliferation, survival, and death.
FGFR调节细胞增殖、生存、分化和迁移等多种功能,在人体发育和成人各项机体功能中发挥重要作用。
FGFR regulates various functions such as cell proliferation, survival, differentiation and migration, and plays an important role in human development and adult body functions.
可是当MOG招致一些T细胞增殖时,有一组CD8+T细胞对任何肽都不有反馈。
But while MOG caused some T cells to proliferate, there was a group of CD8 T cells that didn't respond to any of the peptides.
Ras、PI(3)K和mTOR就是一类与细胞增殖紧密相关的蛋白激酶。
Ras, PI(3)K and mTOR are a class of protein kinases closely related to cell proliferation.
Mills实验室正在努力鉴定出可能通过阻止成熟细胞增殖和分裂来阻止癌前病变的药物。
The Mills lab is working now to identify drugs that may block the precancerous condition by preventing mature cells from proliferating and dividing.
与该家族的其他成员一样,它显示酪氨酸蛋白激酶活性,其对于控制细胞增殖和分化是重要的。
Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
现在发现其也是抗癌药,阻止细胞增殖或迁移。
Now we see it is also anticancer, stopping the cells from proliferating or migrating.
基因组的某些部分包含'癌症驱动因素',其中DNA的变化可以使肿瘤细胞增殖,”福斯特说。
There are parts of the genome that contain‘cancer drivers,' where changes in the DNA can allow tumour cells to proliferate,” Foster said.
这通常是因为细胞的遗传物质(DNA)的变化,尤其是涉及到细胞增殖和修复的基因突变。
This usually happens because of changes in a cell's genetic material(DNA), especially mutations involving genes that play a role in cell multiplication and repair.
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