The researchers discovered that IFITM3 prevents efficient dissemination and replication of influenza virus in heart tissue, thereby limiting cardiac fibrosis and electrical dysfunction during infection.
布朗说:“我们致力于开发新一代平台,使其能够与生物组织(如皮肤、神经和心脏组织)相结合。
Brown further said,‘We are focused on developing next-generation platforms that can integrate with biological tissue(e.g., skin, neural and cardiac tissue).'.
Beshiri added: The World Heart Organization estimates that 17.9 million individuals die from cardiovascular disease every year, and 85% are due to heart attacks and strokes.
Heart disease remains the leading cause of death worldwide, yet the few available treatments are still mostly unsuccessful once the heart tissue has suffered damage.
Beshiri added:“The World Heart Organization estimates that 17.9 million people die from cardiovascular disease each year, and 85% are due to heart attacks and strokes.
The chip contains multiple wells, each with separate tissues and integrated sensors, allowing researchers to study many engineered cardiac tissues at once.
这些效应级联上升,最初影响心脏组织,然后影响心脏,并最终(在心脏攻击的情况下)影响整个身体的健康。
These effects cascade upward, affecting heart tissues, then the heart, and finally(in the event of a heart attack) the health of the whole body.
The heart-on-a-chip contains several wells that each contain separate tissues and integrated sensors, which allows the researchers to study multiple cardiac tissues at one time.
The chip contains multiple wells, each with separate tissues and integrated sensors, which allows researchers to study many engineered cardiac tissues at once.
The chip contains multiple wells, each with separate tissues and integrated sensors, allowing researchers to study multiple engineered cardiac tissues at once.
In particular, they were interested in 5-aminovaleric acid betaine(5-AVAB), which is known to accumulate in particularly active tissues, such as cardiac tissue.
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