For each, researchers calculated a normalized chromosome denominator quality(NCDQ), which measures the likelihood that a sample has the standard two copies of each chromosome.
Niemann- Pick disease is inherited in an autosomal recessive pattern, which means both copies, or alleles, of the gene must be defective to cause the disease.
Because humans carry 2 copies of each gene, left to chance, around half of the 58 embryos the researchers created would have carried the mutated copy..
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