这是一个大问题 in English translation

• it's a big deal
• it's a big problem
• that's a big issue
• this is a major issue
• that's a great question
• that's a big question
• it is a big deal
• it's a huge problem

Examples of using 这是一个大问题 in Chinese and their translations into English

对大多数消费者来说，这是一个大问题。
For most consumers, however, this is a huge problem.

但尽管如此，在纽约市，这是一个大问题。
In New York City, that's a big deal.

将来我们吃的猪肉从哪里来，这是一个大问题。
But I come from a family where pork is a BIG deal.

就个人而言，我不认为这是一个大问题。
Personally, I don't think this is a big issue.

但尽管如此，在纽约市，这是一个大问题。
In New York City, this is a big problem.

但是对雷吉·布什来说，这是一个大问题。
And for Chuck Schumer, that's a big deal.

我认为这是一个大问题，”他回忆起去年在电视上观看季后赛的比赛。
I think it's a big deal," he said, recalling watching last year's playoff games on TV.

这是一个大问题，是世界问题，会解决的。
It's a big problem, it's a world problem and it will be solved.

你可以自己谷歌差异，因为这是一个大问题（显然）。
You can Google the difference yourself, because it's a big deal(apparently).

这是一个大问题,特别是如果一个孩子有分流-或塑料管-植入,以帮助排出过剩的液体。
It's a big problem, especially if a child has a shunt- or plastic tube- implanted to help drain the excess fluid.

这是一个大问题，非常重要，”蒙哥马利谈到巡回赛的第一次访问日本.
It's a big deal, a very big deal," Montgomerie said about tour's first visit to Japan.

因而，这是一个大问题，我们需要剧院老板为此加紧努力，以允许剧院放映叙事电影。
That's a big issue and we need theatre owners to step up, to allow theatres to show films that are narrative films.”.

DEMOKRITOU:这是一个大问题，尤其是在医疗体系支离破碎的发展中国家。
DEMOKRITOU: It's a big problem, especially in developing countries with fragmented health care systems.

他说:“这是一个大问题，治疗方法也不是很好，因为它们会带来巨大的副作用。
It's a huge problem and the treatments are not very good, because they come with huge side-effects.”.

这是一个大问题，非常重要，”蒙哥马利谈到巡回赛的第一次访问日本.
It's a big deal, a very big deal,” said Montgomerie when asked about his tour's first visit to Japan.

然而,这种关系是为了建立共同的价值观、期望和信任,这是一个大问题。
And yet the relationship is about building shared values, expectations, and trust and that's a big issue.

这是一个大问题，因为如果它不能正常工作，人们就会被杀死。
It's a big deal, because if it doesn't work right, people get killed.”.

STEPHANOPOULOS：我-我知道你认为这是一个大问题，但我还没有听到你将如何做的具体细节.
STEPHANOPOULOS: I-- I understand that you think it's a huge problem, but I still don't hear specifics on how you're going to do this.

但是如果你在几十年的时间尺度上看到这样巨大的变化，就会发现这是一个大问题。
But if you see dramatic changes on the order of a few decades, it's a big problem.

这意味着中国近一半的出口到美国的关税，这是一个大问题。
That would mean tariffs on nearly half of China's exports to the US and that's a big issue.