PRIMJENE JEDNOKRATNE DOZE in English translation

• administration of a single dose

Examples of using Primjene jednokratne doze in Croatian and their translations into English

Značajno povišena protutijela(mjereno ELISA-om) na sve serotipove cjepiva opažena su nakon primjene jednokratnih doza Prevenara djeci u dobi od 2 do 5 godina.
Significant increases in antibody(measured by ELISA) to all vaccine serotypes were seen after administration of single doses of Prevenar to children aged 2 to 5 years.

Primjena jednokratnih doza od 300 do 2400 IU/kg epoetina alfa supkutano pokazala je linearnu povezanost srednje vrijednosti Cmax
Administration of single doses of 300 to 2,400 IU/kg subcutaneous epoetin alfa resulted in a linear relationship between mean Cmax

U početnim ispitivanjima sa zdravim dobrovoljcima, primjena jednokratne doze posakonazola infuzijom tijekom 30 minuta kroz periferni venski kateter bila je povezana s incidencijom reakcija na mjestu infuzije od 12% incidencija tromboflebitisa bila je 4.
In initial studies of healthy volunteers, administration of a single dose of posaconazole infused over 30 minutes via a peripheral venous catheter was associated with a 12% incidence of infusion site reactions 4% incidence of thrombophlebitis.

Farmakokinetički parametri odreĎeni su nakon primjene jednokratnih doza od 200 mg emtricitabina, u obliku tvrdih kapsula, u 30 ispitanika koji nisu bili inficirani virusom HIV-a, a imali su različite stupnjeve insuficijencije bubrega.
Pharmacokinetic parameters were determined following administration of a single dose of 200 mg emtricitabine hard capsules to 30 non-HIV infected subjects with varying degrees of renal insufficiency.

Farmakokinetički parametri određeni su uglavnom nakon primjene jednokratnih doza pojedinačnih preparata od 200 mg emtricitabina
Pharmacokinetic parameters were determined following administration of single doses of the individual preparations of emtricitabine 200 mg

U otvorenom kliničkom ispitivanju faze I u kojem se ispitivala primjena jednokratne doze gefitiniba od 250 mg bolesnicima s blagim,
In a phase I open-label study of single dose gefitinib 250 mg in patients with mild,

Nakon primjene jednokratnih doza do 966 mikrograma i višestrukih doza do 290 mikrograma linaklotida,
Following single doses of up to 966 micrograms and multiple doses up

je primjena jednokratne doze od 400 mg nilotiniba koristeći 2 tvrde kapsule od 200 mg kod kojih je sadržaj svake tvrde kapsule pomiješan u jednoj čajnoj žličici kaše od jabuke bioekvivalentna primjeni jednokratne doze od 2 neotvorene tvrde kapsule od 200 mg.
using 2 hard capsules of 200 mg whereby the content of each hard capsule was dispersed in one teaspoon of apple sauce, was shown to be bioequivalent with a single-dose administration of 2 intact hard capsules of 200 mg.

Međutim, u telemetrijskom ispitivanju u pasa nije opaženo da je ivakaftor izazvao produženje QT intervala kod primjene jednokratnih doza do 60 mg/kg, kao ni u mjerenjima EKG-a u ispitivanjima ponovljene doze u pasa u trajanju do 1 godine kod razine doze od 60 mg/kg na dan Cmax nakon 365 dana 36,
However, no ivacaftor-induced QT prolongation was observed in a dog telemetry study at single doses of up to 60 mg/kg or in ECG measurements from repeat-dose studies of up to 1 year's duration at the 60 mg/kg/day dose level

Nakon primjene jednokratne doze do 250 mikrograma/kg u zdravih je dobrovoljaca primijećena skoro linearna farmakokinetika proporcionalna dozi.
Approximately dose-linear pharmacokinetics were observed in healthy volunteers after single dose administration up to 250 micrograms/kg.

Srednji prividni ukupni klirens levofloksacina nakon sistemske primjene jednokratne doze od 500 mg iznosio je 175+/- 29, 2 ml/min.
The mean apparent total body clearance of levofloxacin following systemic administration of a 500 mg single dose was 175+/- 29.2 ml/min.

Nakon intravenske primjene jednokratne doze ceftolozana/tazobaktama od 1 g/0, 5 g u zdravih odraslih muškaraca, više od 95% ceftolozana izlučilo se urinom u neizmijenjenom izvornom obliku.
Following administration of a single 1 g/ 0.5 g IV dose of ceftolozane/tazobactam to healthy male adults greater than 95% of ceftolozane was excreted in the urine as unchanged parent substance.

Nakon primjene jednokratne doze od 375 do 1875 mg uz obrok izloženost(AUC) telapreviru povećala se malo više nego proporcionalno u odnosu na dozu,
The exposure(AUC) to telaprevir increased slightly greater than proportionally to the dose after single-dose administration of 375 up to 1,875 mg with food,

Hemodijaliza započeta dva sata nakon primjene jednokratne doze apiksabana od 5 mg smanjila je AUC apiksabana za 14% u bolesnika u terminalnoj fazi bubrežne bolesti,
Haemodialysis, started two hours after administration of a single dose of apixaban 5 mg, decreased apixaban AUC by 14% in these ESRD subjects, corresponding to an apixaban dialysis

Nakon primjene jednokratne doze od 8 odnosno 10 mg/kg, prosječna izloženost(AUC0-∞) bila je oko 429 odnosno 550 μg*hr/ml, koja je slična izloženosti opaženoj u odraslih pri dozi od 4 mg/kg dose u stanju dinamičke ravnoteže 495 μg*hr/ml.
The mean exposure(AUC0-∞) was approximately 429 and 550 μg*hr/ml after the administration of 8 and 10 mg/kg single doses, respectively, similar to the exposure seen in adults at the 4 mg/kg dose at steady state 495 μg*hr/ml.

Koncentracije posakonazola u plazmi nakon intravenske primjene jednokratne doze posakonazol koncentrata za otopinu za infuziju bile su povećane u rasponu većem od 50 do 200 mg
Posaconazole plasma concentrations following administration of posaconazole concentrate for solution for infusion single dose increased in a greater than dose proportional manner over the range of 50-200 mg; by comparison,

Farmakokinetički parametri tenofovira određeni su nakon primjene jednokratne doze tenofovirdizoproksila od 245 mg u 40 odraslih pacijenata koji nisu bili zaraženi virusom HIV-a
Pharmacokinetic parameters of tenofovir were determined following administration of a single dose of tenofovir disoproxil 245 mg to 40 non-HIV, non-HBV infected adult

Nakon primjene jednokratne doze paracetamola od 1000 mg AUC
Following administration of a single dose of paracetamol 1000 mg,

Nakon primjene jednokratne doze Odomza(100 mg do 3000 mg)
Following the administration of a single dose of Odomzo(100 mg to 3000 mg)

Kinetička ispitivanja nakon primjene jednokratne doze i kontinuiranog liječenja nisu pokazala da se lijek akumulira.
Kinetic studies following the administration of a single dose and continuous treatment have demonstrated that the drug does not accumulate.