CASPOFUNGIN in English translation

• caspofungin

Examples of using Caspofungin in Danish and their translations into English

Det aktive stof i Cancidas, caspofungin, tilhører en gruppe svampemidler, der kaldes' echinocandiner.
The active substance in Cancidas, caspofungin, belongs to a group of antifungal medicines known as‘ echinocandins.

Mere end 7 dages behandling med caspofungin, havde 50%(26/ 52) gunstigt respons.
For those patients who received more than 7 days of therapy with caspofungin, 50%(26/ 52) had a favourable response.

In vitro undersøgelser viser, at caspofungin ikke hæmmer cytokrom P450 enzymer 1A2,
In vitro studies show that caspofungin is not an inhibitor of cytochrome P450 enzymes 1A2,

Caspofungin er i in vitro undersøgelser negativ med henblik på genotoksicitet, såvel som i in vivo undersøgelser med knoglemarvskromosom hos mus.
Caspofungin was negative in in vitro assays for potential genotoxicity as well as in the in vivo mouse bone marrow chromosomal test.

mycophenolat mofetil administreres sammen med caspofungin.
mycophenolate mofetil are co-administered with caspofungin.

Der er inkluderet 239 patienter i en undersøgelse med henblik på at sammenligne caspofungin med amphotericin B til behandling af invasiv candidiasis.
Two hundred thirty-nine patients were enrolled in a study to compare caspofungin and amphotericin B for the treatment of invasive candidiasis.

fluconazole eller caspofungin.
fluconazole or caspofungin.

Caspofungin udviser moderat non- lineær farmakokinetik med øget akkumulering ved stigende doser,
Caspofungin displays moderate non-linear pharmacokinetics with increased accumulation as the dose is increased,

MIC værdier for caspofungin bør ikke anvendes til at forudsige klinisk resultat,
MIC values for caspofungin should not be used to predict clinical outcome,

To mellemprodukter, dannet under nedbrydningen af caspofungin ved ringåbning, danner kovalente adduktorer til plasmaproteiner,
Two intermediate products, formed during the degradation of caspofungin to this open ring compound, form covalent adducts

Europa- Kommissionen udstedte en markedsføringstilladelse med gyldighed i hele Den Europæiske Union for Caspofungin MSD til Merck Sharp& Dohme Limited den 24. oktober 2001.
The European Commission granted a marketing authorisation valid throughout the European Union for Caspofungin MSD to Merck Sharpe and Dohme Limited on 24 October 2001.

Disse blev behandlet enten med caspofungin 50 mg én gang daglig efter bolusdosis på 70 mg caspofungin
A total of 1111 patients with persistent fever and neutropaenia were enrolled in a clinical study

Til behandling af candidiasis i spiserøret blev Mycamine sammenlignet med fluconazole i en undersøgelse med 518 voksne og med caspofungin i en anden undersøgelse med 452 voksne.
For the treatment of oesophageal candidiasis, Mycamine was compared with fluconazole in one study involving 518 adults, and with caspofungin in another study involving 452 adults.

tolerabilitet samt effekt af caspofungin.
and efficacy of caspofungin.

170% øgning i mindste målte koncentration af caspofungin på den første dag med co- administration når lægemidlerne blev initieret samtidigt hos raske voksne frivillige.
170% increase in trough concentration of caspofungin on the first day of co-administration when both medicinal products were initiated together in healthy adult volunteers.

Caspofungin virker in vitro mod Aspergillusarter Aspergillus fumigatus[N 75], Aspergillus flavus[N 111], Aspergillus niger[N 31], Aspergillus nidulans[N 8], Aspergillus terreus[N 52]
Caspofungin has in vitro activity against Aspergillus species Aspergillus fumigatus[N 75],

havde mild til fremskreden nyreinsufficiens dog ingen betydelig effekt på koncentrationen af caspofungin.
there was no significant effect of mild to advanced renal impairment on caspofungin concentrations.

Nogle raske voksne frivillige, der fik ciclosporin 2 doser á 3 mg/ kg sammen med caspofungin, viste forbigående stigninger i alanin transaminase(ALAT)
Some healthy adult volunteers who received two 3 mg/ kg doses of cyclosporin with caspofungin showed transient increases in alanine transaminase(ALT)

Der administreredes, efter en bolusdosis på 70 mg, caspofungin 50 mg, én gang dagligt, mens amphotericin B administreredes med 0, 6- 0, 7 mg/ kg/
Caspofungin 50 mg once daily was administered following a 70 mg loading dose,

intention til at behandle) effekt analyse af generelt fordelagtigt respons; caspofungin(33, 9%) var lige så effektivt som liposomal amphotericin B(33, 7%)% forskel 0, 2 95, 2% CI- 5, 6, 6.
efficacy analysis of overall favourable response; caspofungin(33.9%) was as effective as liposomal amphotericin B(33.7%)% difference 0.2 95.2% CI- 5.6.