Examples of using Dasatinib in English and their translations into German
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Financial
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Ecclesiastic
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Political
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Computer
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Programming
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Official/political
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Political
Treatment with dasatinib is associated with anaemia,
CYP3A4 is a major enzyme responsible for the metabolism of dasatinib.
Irinotecan, dasatinib, nilotinib, vinblastine
Tyrosine kinase inhibitors such as dasatinib and nilotinib, also vincristine and vinblastine.
The efficacy of dasatinib is based on haematological
Dasatinib acts mainly by blocking the protein kinase called‘ BCR-ABL' kinase.
Dasatinib is a substrate
Dasatinib was clastogenic in vitro to dividing Chinese Hamster Ovary(CHO) cells.
Dasatinib, nilotinib, paclitaxel,
The overall mean terminal half-life of dasatinib is approximately 5-6 hours in patients.
Durability of response and estimated survival rates provide additional evidence of dasatinib clinical benefit.
The recommended starting dose for chronic phase CML is 100 mg dasatinib once daily.
A total of 387 patients received dasatinib 70 mg twice daily 288 resistant and 99 intolerant.
In case of therapy failure, the conversion to dasatinib might be temporarily successful.
Concomitant use of dasatinib and a CYP3A4 substrate may increase exposure to the CYP3A4 substrate.
Clinically relevant interactions Dasatinib is a substrate
The pharmacokinetics of dasatinib were evaluated in 229 adult healthy subjects and in 84 patients.
It cannot be excluded that the effect is larger after multiple doses of dasatinib.
Main Function: Dasatinib is a cancer drug.
Dasatinib and nilotinib can also be used as first line therapy instead of imatinib.