Examples of using Efflux in English and their translations into Hungarian
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Medicine
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is transported by OATP1B3, and efflux transported by P-gp and BCRP.
Other resistance mechanisms such as permeation barriers(common in Pseudomonas aeruginosa) and efflux mechanisms may also effect susceptibility to moxifloxacin.
is a substrate for p- glycoprotein(P-gp) efflux in vitro.
Reduced bacterial permeability(common in P. aeruginosa) and efflux mechanisms may also confer or contribute to resistance.
Retapamulin MICs of 2-64 µg/ml have been reported for clinical isolates of S. aureus possessing either the efflux or cfr resistance mechanisms described above.
inducers of CYP3A4 or PgP may decrease everolimus blood concentrations by increasing metabolism or the efflux of everolimus from intestinal cells.
when the mechanism is, or includes, impermeability to some compounds and/or an efflux pump.
the co-administered substance for CYP3A and P-gp, and the extent of intestinal first-pass metabolism/efflux.
Lapatinib has also been shown in vitro to inhibit these efflux transporters, as well as the hepatic uptake transporter OATP 1B1, at clinically relevant concentrations(IC50 values were equal to 2.3 µg/ ml).
ribosomal protection and efflux.
in part, to a relatively slow efflux of docetaxel from the peripheral compartment.
Other resistance mechanisms such as permeation barriers(common in Pseudomonas aeruginosa) and efflux mechanisms may also affect susceptibility to levofloxacin.
was transported by OATP1B1 and OATP1B3, and efflux transported by BCRP,
Due to poorer permeability and increased efflux of naloxegol across the blood-brain barrier, related to P-gp substrate properties, the CNS penetration of naloxegol is minimal.
Impermeability and/ or active substance efflux pump mechanisms of resistance may have a variable effect on susceptibility to fluoroquinolones, which depends on the physiochemical
However, in vitro tafamidis meglumine inhibits the efflux transporter BCRP(breast cancer resistant protein)
In addition, caution should be taken when pixantrone is continuously co-administered with efflux transport inducers such as rifampicin,
expression of efflux pump, or mutation of enzymes responsible for the molecule' s binding site.
and OCT2) and efflux transporters(P-gp and BCRP)
possibly due to saturation of metabolic pathways or efflux transporters.