Examples of using Ames test in English and their translations into Italian
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Tenofovir disoproxil fumarate was positive in the Ames test(strain TA 1535)
In vitro genotoxicity test approved by the EU include among others the bacterial reverse mutation test( Ames test), the E. coli reverse mutation assay,
specific studies with cysteamine did not show any mutagenic effects in the Ames test or any clastogenic effect in the mouse micronucleus test. .
specific studies with cysteamine bitartrate did not show any mutagenic effects in the Ames test or any clastogenic effect in the mouse micronucleus test. .
Collagenase clostridium histolyticum was not mutagenic in Salmonella typhimurium(AMES test) and was not clastogenic in both an in vivo mouse micronucleus assay
Pegaspargase was not mutagenic in the Ames test using Salmonella typhimurium strains.
In one single genotoxicity study(Ames test), no mutagenic effect has been observed.
Tests of genotoxicity in vitro were either negative(Ames test, chromosomal aberration test)
Results indicate that sodium phenylbutyrate did not induce any mutagenic effects in the Ames test with or without metabolic activation.
Capecitabine was not mutagenic in vitro to bacteria(Ames test) or mammalian cells Chinese hamster V79/ HPRT gene mutation assay.
Cabazitaxel did not induce mutations in the bacterial reverse mutation(Ames) test.
Dasatinib was not mutagenic in in vitro bacterial cell assays(Ames test) and was not genotoxic in an in vivo rat micronucleus study.
Ferric citrate was neither mutagenic in the bacterial reverse mutation assay(Ames test) nor clastogenic in the chromosomal aberration test in Chinese hamster fibroblasts.
Epoetin alfa does not induce bacterial gene mutation(Ames Test), chromosomal aberrations in mammalian cells,
Carbaglu showed no significant mutagenic activity in a battery of genotoxicity tests performed in vitro(Ames test, human lymphocyte metaphase analysis) and in vivo micronucleus
A bacterial reverse mutation assay study(“Ames test”) was performed with the cysteamine bitartrate used for PROCYSBI
Carfilzomib was not mutagenic in the in vitro bacterial reverse mutation(Ames) test and was not clastogenic in the in vivo mouse bone marrow micronucleus assay.
Imatinib was not considered genotoxic when tested in an in vitro bacterial cell assay(Ames test), an in vitro mammalian cell assay(mouse lymphoma)
Peginterferon beta-1a was not mutagenic when tested in an in vitro bacterial reverse mutation(Ames) test and was not clastogenic in an in vitro assay in human lymphocytes.
Tests of genotoxicity in vitro were negative(Ames test, chromosomal aberration test)