Examples of using Avanafil in English and their translations into Italian
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Colloquial
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Official
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Medicine
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Financial
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Ecclesiastic
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Ecclesiastic
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Computer
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Programming
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Official/political
 Drug interaction Do not take at the same time with similar medications that increase potency such as avanafil(Stendra), tadalafil(Cialis) or vardenafil(Levitra).
Stop using avanafil and call your doctor at once if you have any of these serious side effects.
Renal dialysis is not expected to accelerate clearance as avanafil is highly bound to plasma proteins
In total, 7/24 subjects experienced values or decreases from baseline that were of potential clinical significance following avanafil dosing see section 4.4.
The potential induction of CYP1A2, CYP2B6 and CYP3A4 by avanafil evaluated in primary human hepatocytes in vitro did not reveal any potential interaction at clinically relevant concentrations.
Taking avanafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Taking avanafil with a nitrate medicine for chest pain
Avanafil works by increasing blood flow to the penis to help a man get
Stop using avanafil and get emergency medical help if you have sudden vision loss.
Provided you don't have particular circulatory issues they are«safer than aspirin»(his words), and avanafil in particular solved two issues typical of its competitors.
Patients should be advised to avoid grapefruit juice within 24 hours prior to taking avanafil.
This is thought to result from the combined effects of nitrates and avanafil on the nitric oxide/cGMP pathway.
including grapefruit juice would likely increase avanafil exposure.
Amlodipine(5 mg daily) increased avanafil 200 mg single-dose Cmax and AUC by approximately 28% and 60%, respectively.
Studies have shown that medicinal products that inhibit CYP3A4 can increase avanafil exposure see section 4.2.
All these drugs target an enzyme called PDE5,and avanafil appears to inhibit this enzyme more selectively than the other.
In a patient who has taken avanafil within 12 hours,
Consequently, the maximum recommended dose of avanafil is 100 mg, not to exceed once every 48 hours for patients taking concomitant moderate CYP3A4 inhibitors see section 4.2.
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA
Patients were initially assigned to avanafil 100 mg and at any point during the trial, they could request to have their dose of avanafil increased to 200 mg or decreased to 50 mg based on their individual response to treatment.