Examples of using Glucuronide in English and their translations into Slovak
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Medicine
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the metabolites are excreted as glucuronide conjugates.
The maltol appeared to be rapidly metabolised to maltol glucuronide(Cmax= 4677+ 1613 ng/mL).
the most abundant metabolites were three glucuronide conjugates(2-, 3-, and 6-O glucuronide). .
Nomegestrol acetate and its hydroxylated metabolites undergo extensive phase 2 metabolism to form glucuronide- and sulphate conjugates.
the metabolites are excreted as glucuronide conjugates.
CYP1A2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine
Dapagliflozin: The metabolism of dapagliflozin is primarily via glucuronide conjugation mediated by UDP glucuronosyltransferase 1A9(UGT1A9).
Of the ingested dose is eliminated via the kidneys within 24 hours, principally as glucuronide(60 to 80%) and sulphate conjugates(20 to 30%).
Renal excretion of the glucuronide(and possibly zidovudine itself) is reduced in the presence of probenecid.
Metabolism by glucuronide conjugation is the primary mechanism of clearance for nalmefene,
Thus cytochrome P450 metabolism, glucuronide conjugation, and urinary excretion of glucuronidated metabolites represent the primary route of nevirapine biotransformation and elimination in humans.
The terminal half-life of parent drug and its glucuronide is approximately 11 hours and 18 hours.
However, accumulation of the glucuronide metabolite is to be expected; caution should therefore be exercised in treating patients with renal failure.
was a glucuronide conjugate of tipranavir.
of total ezetimibe(ezetimibe+ ezetimibe glucuronide) approximately 55%.
estriol are excreted in the urine, along with glucuronide and sulfate conjugates.
1A2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine
minor amounts of the phase II metabolites, glucuronide and sulfate conjugates, were observed.
enterohepatic cycling of raloxifene and its glucuronide metabolites.
enhance the elimination of the glucuronide metabolite.