Voorbeelden van het gebruik van An inducer in het Engels en hun vertalingen in het Nederlands
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Rifampicin(600 mg daily), a potent inducer of CYP3A and CYP2B6, and an inducer of CYP2C9, CYP2C19, and CYP2C8, did not significantly change the pharmacokinetics of prasugrel.
it cannot be excluded that vismodegib upon longer treatment is an inducer of enzymes which metabolise contraceptive steroids.
is not an inducer of CYP3A4 and CYP1A2.
the absence of auto- induction upon multiple dosing in patients indicates that cinacalcet is not an inducer of CYP3A4, CYP1A2
and CYP3A4 nor an inducer of CYP1A2, CYP2C19 and CYP3A4.
is not an inducer of CYP 1A2 and 3A4.
Conversely, cessation of treatment of an inducer might lead to increased plasma levels of febuxostat.
Rifampicin, which is an inducer of P-gp, reduced aliskiren bioavailability by approximately 50% in a clinical study.
In vitro data indicate that selexipag could be an inducer of both CYP3A4 and CYP2C9 in the intestine.
Bosentan is an inducer of CYP2C9 and CYP3A4 and possibly also of CYP2C19 and the P-glycoprotein.
However, it is unknown whether carfilzomib is an inducer of CYP1A2, 2C8, 2C9, 2C19 and 2B6 at therapeutic concentrations.
Co-administration of pioglitazone with rifampicin(an inducer of cytochrome P450 2C8)
Nevirapine is an inducer of CYP3A and potentially CYP2B6,
Co- administration of pioglitazone with rifampicin(an inducer of cytochrome P450 2C8)
In vitro studies indicate that eluxadoline is neither an inducer of CYP1A2, CYP2B6,
These results indicate that raltegravir is not an inducer or inhibitor of CYP3A4,
The interaction potential of dalbavancin on medicinal products metabolised by CYP enzymes is expected to be low since it is neither an inhibitor nor an inducer of CYP enzymes in vitro.
Trametinib was found to be an in vitro inhibitor of CYP2C8, CYP2C9 and CYP2C19, an inducer of CYP3A4 and an inhibitor of the transporters OAT1,
under conditions of clinical use, enzalutamide may be an inducer of P-gp via activation of the nuclear pregnane receptor PXR.
or with rifampicin(an inducer of cytochrome P450 2C8)