Примери за използване на Glucuronide на Английски и техните преводи на Български
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enterohepatic cycling of raloxifene and its glucuronide metabolites.
The concentrations of this glucuronide are approximately 10-fold higher than those of unchanged BZA in plasma.
The terminal half-life of parent drug and its glucuronide is approximately 11 hours
to form ambrisentan glucuronide(13%).
Raloxifene undergoes extensive first pass metabolism to the glucuronide conjugates: raloxifene-4'- glucuronide, raloxifene-6-glucuronide, and raloxifene-6, 4′-diglucuronide.
Metabolism by glucuronide conjugation is the primary mechanism of clearance for nalmefene,
Glucuronide and/or sulfate conjugates of glycopyrronium were found in urine of humans after repeated inhalation,
Sulfate and glucuronide metabolites do not bind to plasma proteins even at relatively high concentrations.
1A2 catalyse the formation of the two major metabolites glucuronide conjugate of 4-hydroxy duloxetine
The glucuronide and sulfate conjugates of pregnanediol
The 5'-glucuronide of zidovudine is the major metabolite in both plasma
The sulphate and glucuronide metabolites do not bind to plasma proteins even at relatively high concentrations.
Peak serum concentrations of the glucuronide occur 2 to 3 hours after administration of deferiprone.
Peak serum concentrations of the glucuronide occur 2 to 3 hours after administration of deferiprone.
Renal excretion of the glucuronide(and possibly zidovudine itself)
The metabolism of dapagliflozin is primarily via glucuronide conjugation mediated by uridine diphosphate(UDP) glucuronosyltransferase 1A9(UGT1A9).
primarily by glucuronide conjugation, and excreted in the urine.
its hydroxylated metabolites undergo extensive phase 2 metabolism to form glucuronide- and sulphate conjugates.
Raloxifene comprises less than 1% of the combined concentrations of raloxifene and the glucuronide metabolites.
Greater than 80% of the radioactivity in urine was made up of glucuronide conjugates of hydroxylated metabolites.