Примери за използване на Kinases на Английски и техните преводи на Български
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The researchers' work showed that ABL kinases induce cathepsin expression
Ruxolitinib is a selective inhibitor of the Janus Associated Kinases(JAKs) JAK1
Their work showed that ABL kinases induce cathepsin expression
is phosphorylated by cellular kinases to stavudine triphosphate which inhibits HIV reverse transcriptase by competing with the natural substrate, thymidine triphosphate.
This means that it blocks the activity of enzymes known as tyrosine kinases, particularly tyrosine kinases that are present in EGFRs.
most tyrosine kinases inhibitors such as dasatinib
This means that it blocks the action of certain enzymes known as receptor tyrosine kinases.
Preclinical data generated in biochemical assays demonstrated that dabrafenib inhibits BRAF kinases with activating codon 600 mutations(Table 5).
for activation via thymidine kinases.
the study showed new evidence linking the activation of ABL kinases- cancer-promoting genes- to the secretion of pro-metastatic cathepsins in melanoma.
Preclinical data generated in biochemical assays demonstrated that vemurafenib can potently inhibit BRAF kinases with activating codon 600 mutations(table 6).
Lastly, the researchers found that ABL kinases inhibitors already approved by the Food& Drug Administration for treating leukemia also prevented metastasis induced by secreted cathepsins in animal models of metastatic melanoma.
SRC family kinases along with a number of other selected oncogenic kinases including c-KIT,
This study is the first to demonstrate that ABL kinases not only increase the abundance of the transcription factors,
specificity of protein kinases are considered as initial triggers for the transformation of a normal cell into a tumor cell.
activation of alternate signaling pathways involving the SRC family kinases(LYN, HCK),
the Abl protein tyrosine kinases as a consequence of fusion to diverse partner proteins
activation of alternate signalling pathways involving the SRC family kinases(LYN, HCK),
as drugs that inhibit ABL kinases have been used for decades to treat leukemia with few side effects," said Rakshamani Tripathi,
High levels of the muscle protein creatine kinase(CK).