Примери за използване на Therapeutic index на Английски и техните преводи на Български
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If a narrow therapeutic index P-gp or BCRP substrate must be used, it should be used with caution.
administered with individually titrated, narrow therapeutic index medications that are predominantly metabolised by CYP2D6.
As the therapeutic index for digoxin is very narrow, it is advisable
flavonoids can inhibit THC's intoxicating effects while increasing the therapeutic index of the substance at the same time.
just be a few times larger than the prescribed dose, the“therapeutic index” for cannabis is like 40,000 to 1.
Dr. Ethan Russo further confirms this theory with scientific evidence by demonstrating that terpenes serve as inhibitors for the intoxicating effects of THC and increase the therapeutic index of THC.
thereby increasing THC's therapeutic index.
thereby increasing THC's therapeutic index.
administered with individually titrated, narrow therapeutic index substances that are predominantly metabolised by CYP2D6(e.g.,
Given that digoxin has a narrow therapeutic index, it is recommended that the lowest possible dose of digoxin should initially be prescribed in case digoxin is given to patients on boosted darunavir therapy.
Given that digoxin has a narrow therapeutic index, it is recommended that the lowest possible dose of digoxin should initially be prescribed in case digoxin is given to patients on darunavir/ritonavir therapy.
administered with individually titrated, narrow therapeutic index substances that are predominantly metabolised by CYP2D6(e. g.,
administered with individually titrated, narrow therapeutic index substances that are predominantly metabolised by CYP2D6(e.g. flecainide,
Given that digoxin has as a narrow therapeutic index, it is recommended that the lowest possible dose of digoxin should initially be prescribed
administered with individually titrated, narrow therapeutic index substances that are predominantly metabolised by CYP2D6(e.g. flecainide,
Therefore, administering siltuximab with CYP450 substrates that have a narrow therapeutic index has the potential to change therapeutic effects
Medicinal products that have a narrow therapeutic index and are largely dependent on the hepatic cytochrome P450 system for clearance,
The CHMP agreed with the EWP PK expert group position that if ciclosporin is considered a narrow therapeutic index drug, a narrowed(90-111%) acceptance range should
Caution and monitoring for toxicity are advised during concomitant treatment with sensitive substrates of these transporters which exhibit a narrow therapeutic index, including but not limited to digoxin,
breast cancer resistance protein(BCRP) observed with abemaciclib, in vivo interactions of abemaciclib with narrow therapeutic index substrates of these transporters, such as digoxin or dabigatran etexilate, may occur.