It results from the fusion of two chromosomes and contains elements of what are known as transcription factors, which activate the transcription of certain genes.
RB1基因的产物pRB的经典功能是抑制E2F转录因子家族。
The canonical function of the RB1 gene product RB1 is to repress the E2F transcription factor family.
基因调控”可以由来自环境或其他细胞的电磁信号控制,这些电磁信号会激活称为“转录因子”的蛋白质。
Gene regulation can be controlled by electromagnetic signals coming from the environment or from other cells that activate proteins called transcription factors.
Thus far, the best data available on the components downstream of this pathway are from experiments involving the Caenorhabditis elegans FOXO transcription factor, DAF-16;
这些蛋白和DNA上的精确位点结合以充当路标,告诉转录因子其目标基因就在附近。
These proteins bind to precise sites on the DNA that serve as guideposts, telling transcription factors that their target genes are nearby.
研究人员报告称,从机制上讲,造血系统的这些改变,似乎与被称为Gfi1的转录因子过量表达有关。
The team also noted that these alterations of the body's blood-making system appear to be linked to over-expression of a transcription factor called Gfi1.
然而,在癌症病例中,研究人员不确定转录因子在肿瘤生长中的作用。
However, in the case of cancer, researchers were unsure of the role that this transcription factor had in tumor growth.
这一结果说明BCL11A在SOX-2信号通路带来的转录因子改变中起到部分调节作用。
This result indicates that BCL11A plays a partial regulatory role in the transcription factor changes brought about by the SOX-2 signaling pathway.
作为一种转录因子,Onecut2是身体产生某些蛋白所需的。
Onecut2, a type of transcription factor, is necessary for the body to produce certain proteins.
The findings revealed the complete subunit organization of a transcription factor called TFIIH, which has a critical role in opening the promoter region.
它的功能作为一个转录因子,regulates特定靶基因的转录。
It functions as a transcription factor that regulates transcription of specific target genes.
Morris水迷宫训练提高了小鼠海马转录因子核因子(红系衍生2)-2和核因子κBp65水平。
Morris water maze training in mice elevates hippocampal levels of transcription factors nuclear factor(erythroid-derived 2)-like 2 and nuclear factor kappa B p65.
The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines.
NDT80基因产生的蛋白质是一种转录因子,这意味着它会激活其他基因。
The protein produced by the NDT80 gene is a transcription factor, meaning that it activates other genes.
这些基因编码转录因子,在开发过程中结合在其各自的区域中导致组织规格。
These genes code for transcription factors that combine to cause tissue specification in their respective regions during development.
然而,当转录因子改变了它们的作用时,细胞的正常功能也会发生变化,从而导致疾病。
However, when the transcription factors change what they do, the normal functions of the cell can also change, and that can lead to disease.
此外,许多转录因子形成数量惊人的前馈回路,共同调控靶基因。
Further, many of the transcription factors form a surprisingly large number of feed-forward loops that co-regulate target genes.
转录因子在过程中扮演重要角色,为确保在这种速度下,有99.99%的转译正确性。
Elongation factors play a role in orchestrating the events of this process, and in ensuring the 99.99% accuracy of translation at this speed.
当免疫沉淀的蛋白质是一种转录因子时,那么DNA的富集区域就是这种它的转录因子结合位点(TFBS)。
When the protein is a transcription factor, the enriched area is its transcription factor binding site(TFBS).
这些研究结果揭示了TFIIH转录因子完整的亚基组织,TFIIH在开放启动子区域中起关键作用。
The findings revealed the complete subunit organization of a transcription factor called TFIIH, which has a critical role in opening the promoter region.
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