Eksempler på bruk av Relevant concentrations på Engelsk og deres oversettelse til Norsk
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MATE2 at clinically relevant concentrations in vitro.
Based on in vitro studies, the potential risk of inhibition by cabazitaxel at clinically relevant concentrations is possible towards medicinal products that are mainly substrate of CYP3A.
3A4, at clinically relevant concentrations.
2E1 at clinically relevant concentrations.
induce CYP1A2 at clinically relevant concentrations.
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In vitro, crizotinib did not inhibit the human hepatic uptake transport proteins organic anion transporting polypeptide(OATP)1B1 or OATP1B3 or the renal uptake transport proteins organic anion transporter(OAT)1 or OAT3 at clinically relevant concentrations.
2B6, 2C8, 2C9, 2C19, 2D6 and 3A4 at clinically relevant concentrations of idebenone or QS10.
naproxen, diclofenac and piroxicam at clinically relevant concentrations.
CYP2E1 because mirabegron did not inhibit the activity of these enzymes at clinically relevant concentrations.
may cause drug-drug interactions at clinically relevant concentrations with substrates of these transporters e.g. non-steroidal anti-inflammatory drugs,
PK parameter values at clinically relevant concentrations(Cmax and Cmin)
At relevant clinical concentrations, eribulin did not inhibit BCRP, OCT1, OCT2,
Eribulin does not inhibit the CYP enzymes CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6 or 2E1 at relevant clinical concentrations.
MPA at clinically relevant concentrations is 97% bound to plasma albumin.
In vitro, crizotinib is not an inhibitor of BSEP at clinically relevant concentrations.
Lapatinib inhibits CYP2C8 in vitro at clinically relevant concentrations.
At clinically relevant concentrations avanafil is not an inhibitor of OATP1B1, OATP1B3, OCT1, OCT2, OAT1, OAT3 and BSEP.
However it has been shown that at clinically relevant concentrations eribulin is not a Pgp inhibitor in vitro.
Kaletra does not inhibit CYP2D6, CYP2C9, CYP2C19, CYP2E1, CYP2B6 or CYP1A2 at clinically relevant concentrations(see section 4.3).