TALIDOMIDA - prijevod na Engleskom

• thalidomide

Primjeri korištenja Talidomida na Hrvatski i njihovi prijevodi na Engleskom

zabilježenih nakon liječenja talidomidom, PRAC smatra da postoji potvrđena uzročna povezanost između talidomida i plućne hipertenzije.
reported following treatment with thalidomide that there is a confirmed causal association between thalidomide and pulmonary hypertension.

Prikazane učestalosti temelje se na zapažanjima tijekom pivotalnog usporednog kliničkog ispitivanja kojim je ispitivan učinak talidomida u kombinaciji s melfalanom
Frequencies given are based on the observations during a pivotal comparative clinical study investigating the effect of thalidomide in combination with melphalan

Najčešće opažene nuspojave povezane s uporabom talidomida u kombinaciji s melfalanom i prednizonom su:
The most commonly observed adverse reactions associated with the use of thalidomide in combination with melphalan

drugih nuspojava povezanih s uporabom talidomida.
other adverse reactions associated with the use of thalidomide.

tjelesnom težinom od 47-133 kg, klirens talidomida bio je u rasponu od približno 6-12 l/h,
in multiple myeloma patients with body weight from 47-133kg, thalidomide clearance ranged from approximately 6-12 L/h,

postoji potvrđena uzročna povezanost između talidomida i reaktivacije virusa varicella-zoster
that there is a confirmed causal association between thalidomide and varicella-zoster virus

antineoplastični učinci talidomida mogu biti povezani sa supresijom prekomjernog stvaranja čimbenika nekroze tumora alfa( TNF-),
anti-neoplastic effects of thalidomide may be related to suppression of excessive tumour necrosis factor-alpha(TNF-) production, down-modulation of selected

Klinički važne nuspojave povezane s uporabom talidomida u kombinaciji s melfalanom
The clinically important adverse reactions associated with the use of thalidomide in combination with melphalan

Kako bi se osiguralo sprječavanje izlaganja fetusa talidomidu i omogućile dodatne važne sigurnosne informacije,
In order to assist patients in avoiding foetal exposure to thalidomide and to provide additional important safety information,

pod uvjetom da se utvrde vrlo stroge mjere kako bi se izbjeglo izlaganje nerođene djece talidomidu, koristi od lijeka Thalidomide Celgene nadmašuju s njim povezane rizike te je preporučio odobrenje za stavljanje lijeka u promet.
provided that very strict measures are put in place to avoid exposure of unborn children to thalidomide, Thalidomide Celgene's benefits are greater than its risks and recommended that it be given marketing authorisation.

Numana nakon noći šmrkanja talidomida.
After a night of snorting thalidomide. Neuman.

Numana nakon noći šmrkanja talidomida.
Neuman after a night of snorting thalidomide.

U literaturi je zabilježena moguća križna reakcija između lenalidomida i talidomida.
A possible cross-reaction between lenalidomide and thalidomide has been reported in the literature.

Potreban je oprez prilikom primjene talidomida u kombinaciji s lijekovima koji prouzročuju omamljenost.
Caution should be used when thalidomide is given in combination with medicinal products that cause drowsiness.

Zahtjev da bolesnici trebaju biti sposobni pridržavati se zahtjeva za sigurnu primjenu talidomida.
That patients should be capable of complying with the requirements for the safe use of thalidomide.

Nije otkriven mutagen ili genotoksičan učinak prilikom ispitivanja talidomida u seriji standardnih testova genotoksičnosti.
No mutagenic or genotoxic effect has been revealed when thalidomide was assayed in a standard battery of genotoxicity tests.

ozbiljnost periferne neuropatije povećavaju se s istodobnom primjenom bortezomiba ili talidomida.
severity of peripheral neuropathy increase with concomitant bortezomib or thalidomide administration.

rezultirali prekidom primjene talidomida.
resulted in discontinuation of thalidomide.

se upotrebljava u kliničke svrhe kao racemat(+)-(R)- i(-)-(S)- talidomida.
is used clinically as a racemate of(+)-(R)- and(-)-(S)- thalidomide.

Pored toga, primjena pojedinačne doze od 0, 5 mg digoksina nije imala očitog učinka na farmakokinetiku talidomida.
In addition, single dose administration of 0.5 mg digoxin had no apparent effect on thalidomide pharmacokinetics.