DEFERIPRONE in English translation

• deferiprone

Examples of using Deferiprone in Danish and their translations into English

uden seponering eller dosisnedsættelse af deferiprone se afsnit 4. 4.
decreasing the dose of deferiprone see section 4.4.

Eftersom deferiprone kan forbindes med neutropeni
Given that deferiprone can be associated with neutropenia

Der er begrænsede data til rådighed om brugen af deferiprone til børn i alderen fra 6 til 10 år
There are limited data available on the use of deferiprone in children between 6

Til 90% af den indtagne dosis rapporteres som værende genfundet i urinen i løbet af de første 24 timer i form af frit deferiprone, glucuronidmetabolitten og jerndeferipronekompleks.
Deferiprone is eliminated mainly via the kidneys; 75% to 90% of the ingested dose is reported as being recovered in the urine in the first 24 hours, in the form of free deferiprone, the glucuronide metabolite and the iron-deferiprone complex.

Kliniske undersøgelser har vist, at deferiprone er effektivt til fremme af jernudskillelse,
Clinical studies have demonstrated that deferiprone is effective in promoting iron excretion

HIV- positive eller på anden vis immunudsatte patienter Der findes ingen tilgængelige data om anvendelse af deferiprone på patienter, som er HIV- positive eller på anden vis har et defekt immunforsvar.
HIV positive or other immune compromised patients No data are available on the use of deferiprone in HIV positive or in other immune compromised patients.

blevet rapporteret hos patienter, der har modtaget behandling med deferiprone.
have also been reported in patients treated with deferiprone.

Kliniske undersøgelser har vist, at deferiprone er effektivt til fremme af jernudskillelse,
Clinical studies have demonstrated that deferiprone is effective in promoting iron excretion

selv om der ikke var noget fald i mængden af absorberet deferiprone, da det blev givet sammen med føde.
state(126 μ mol/ l), although there was no decrease in the amount of deferiprone absorbed when it was given with food.

Eftersom deferiprone binder sig til metalkationer,
However, since deferiprone binds to metallic cations,

Tag ikke Ferriprox- Hvis De er overfølsom(allergisk) over for deferiprone eller et af de øvrige indholdsstoffer.-
Do not take Ferriprox- if you are allergic(hypersensitive) to deferiprone or any of the other ingredients of Ferriprox.-

Deferiprone Lipomed monoterapi er indiceret til behandling af jernophobning i patienter med thalassaemia major, når de nuværende kelation terapi er kontraindiceret eller utilstrækkelige.
Deferiprone Lipomed monotherapy is indicated for the treatment of iron overload in patients with thalassaemia major when current chelation therapy is contraindicated or inadequate.

Deferiprone Lipomed i kombination med en anden chelator er indiceret hos patienter med thalassaemia major, når monoterapi med nogen strygejern chelator er ineffektive,
Deferiprone Lipomed in combination with another chelator is indicated in patients with thalassaemia major when monotherapy with any iron chelator is ineffective,

Neutropeni/ Agranulocytose Deferiprone har vist sig at forårsage neutropeni, herunder agranulocytose.
Neutropenia/ Agranulocytosis Deferiprone has been shown to cause neutropenia, including agranulocytosis.

Behandling med deferiprone bør ikke indledes, hvis patienten har neutropeni.
Treatment with deferiprone should not be initiated if the patient is neutropenic.

Deferiprone må ikke anvendes af ammende mødre.
Deferiprone must not be used by breast-feeding mothers.

Ved den anbefalede dosering kunne deferiprone derfor være mindre effektiv end deferoxamine.
Therefore deferiprone at the recommended dose could be less effective than deferoxamine.

Biotransformation Deferiprone metaboliseres primært til et glucuronidkonjugat.
Biotransformation Deferiprone is metabolised predominantly to a glucuronide conjugate.

Deferiprone er det aktive stof i Ferriprox.
Deferiprone is the active substance in Ferriprox.

Deferiprone Lipomed indeholder det aktive stof deferipron.
Deferiprone Lipomed contains the active substance deferiprone..