Examples of using Exon in English and their translations into Chinese
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However, the uncommon locations, for example exon 18, tend to respond more strongly to afatinib than to the other first-line TKIs, gefitinib and erlotinib.
Also, mutation of exon 8 of UV radiation resistance-associated gene(UVRAG) reduced autophagy and promoted these cancer types[2, 4].
We found that the coding region of chicken GPR15 was 1 107 bp in length, which was consisted of 1 exon encoding a protein of 368 amino acids.
Together with Piercy's group, Olson and colleagues designed CRISPR's molecular scissors to make a cut at the beginning of exon 51 in the diseased beagles.
In contrast, exon 17/18 mutations stabilize the A loop in an open conformation, which obstructs binding of Type 2 inhibitors(Figure 3A).
Afatinib was used more often in patients with tumors harboring deletion in exon 19(Del19), whereas the gefitinib group had more elderly, females, and never smokers.
Most previous studies had missed exon 4 in the Rest gene because this small exon is not edited into the Rest mRNA in most cells.
Excising certain exons has the potential to correct a majority of DMD mutations.
EGFR mutations normally occur on exons 18 to 21.
Those exons may come from distant locations, even from different chromosomes.
If one or more exons are disrupted or removed by a genetic mutation, the chain is not built, causing the muscle to deteriorate slowly.
Only some DNA nucleotides, however, code for amino acids; these nucleotides are known as"exons.".
Sometimes exons are removed, too, and this can have a major impact on phenotypes, including neurological disorders and cancers.
The DNA of a gene is very long, and specific locations along that stretch are indicated by a system of numbered“exons.”.
Exons are analogous to the mile markers along a highway that tell you where you are.
There are approximately 180,000 exons which represent less than 2% of the human genome.
DMD mutations can lead to certain exons being deleted, limiting the protein's production.
Exons, by contrast, can be moved around without disrupting the rest of the gene.
These pieces, called exons, are thought to make up 1 percent of a person's genome.
The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20.