Examples of using Microenvironment in English and their translations into Japanese
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Colloquial
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Ecclesiastic
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Programming
If cancer cells outcompete the immune cells for shared nutrients in the tumor microenvironment, then the immune cells will physically not be able to do their job.
Induce normal cells around the tumor(i. e, in the tumor microenvironment) to release substances that suppress immune responses and that promote tumor cell proliferationand survival.
His current research investigates the role of angiogenesis and the microenvironment in tumor development and progression, and the prospects for applying knowledge of cancer mechanisms to the development of more“targeted” therapies.
Induce normal cells around the tumor(i. e, in the tumor microenvironment) to release substances that suppress immune responses and that promote tumor cell proliferation and survival.
Over the past decade, there has been an increasing focus on the relationship between cancer cells and their'microenvironment,' specifically on the cell-to-cell interactions that may promote cancer formation and growth.
While waiting for patent approval, the scientists will study how tumors, or the tumor microenvironment, induce FOXO3 expression as well as how FOXO3 induces this suppressive activity.
In order to understand the complex tissue microenvironment under both physiological and pathological conditions such as cancer, profiling immune checkpoint proteins and phenotypic markers is important.
Watch for new developments on our site over the next few weeks toward creating a favorable tumor microenvironment to encourage natural regression.
In Dr. Arbab's studies on metastasis and the processes behind it, he and his team are focused on"going after that tumor microenvironment.".
In addition, ECM can bind signal molecules like growth factors, mitogens, chemokines and cytokines, which makes the tissue microenvironment suitable for cell proliferation, migration, and differentiation.
And it was recently shown experimentally that restoring the metabolic balance in the tumor microenvironment-- that is, making sure immune cells get their food-- can give them, the predators, back their edge in fighting cancer.
Basically, patients who were receiving the treatment had no TGF-beta in their samples,” Dr. Gulley said, noting that the drug appeared to be trapping the protein and removing it from the tumor microenvironment.
Against the background of growing evidence suggesting that the tumour microenvironment might interfere with effective immune recognition even in the presence of checkpoint inhibitors[19], an ongoing phase I/II trial is evaluating the triple kinase inhibitor nintedanib in combination with nivolumab and ipilimumab in patients with advanced NSCLC 20.
Smart nanomachines of a virus size will autonomously patrol the microenvironments in the body and provide diagnostic and therapeutic services 24 hours a day.
Accurate and stable measurement devices enable close control of the microenvironments surrounding semiconductor tools.
Spread throughout it are small reservoirs of stem cells, nested within supportive microenvironments called niches, which keep a tight rein on this repair process.
We further postulate that the same mechanisms by which hyaluronan regulates stem cell quiescence and differentiation in stem cell niches may block progenitor cell differentiation and maturation in the microenvironments of CNS lesions, thus preventing the repair of the CNS.
We aim to realize a"In-Body Hospitals", which provides necessary diagnosis and treatment inside the required parts of the body at the precise time, by creating"smart nanomachines the size of a virus size, which autonomously patrol the microenvironments in the body". This has been mere science fiction until now, but will be made a reality by self-organization of macromolecules integrated with functionals elements required for pin-point diagnosis and targeted therapy.
Human bone marrow microenvironment.
Fig. Cascade originated from mucin in the tumor microenvironment.