Examples of using Are substrates in English and their translations into Swedish
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Ecclesiastic
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Official/political
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Computer
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Programming
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Political
Metabolite NW-1153 is not a substrate for OCT2, or OAT1, but it is substrate for OAT3.
Medicinal products that are substrates of P-glycoprotein Digitalis glycosides.
Fidaxomicin and the metabolite OP-1118 are substrates of P-gp.
The effects of vemurafenib on medicinal products that are substrates of BCRP are unknown.
Dronedarone can increase exposure of statins that are substrates of CYP 3A4 and/or P-gp substrates. .
In vitro studies have determined that neither tenofovir disoproxil nor tenofovir are substrates for the CYP450 enzymes.
Similarly, saquinavir might also modify the pharmacokinetics of other medicinal products that are substrates for CYP3A4 or P-gp.
For administration of medicinal products that are substrates of CYP3A4 with a narrow therapeutic range, see section 4.5.
Co-administration of Epclusa with medicinal products that are substrates of these transporters may increase the exposure of such medicinal products.
Many anticancer medicinal products are substrates of BCRP and therefore there is a theoretical risk for an interaction with vemurafenib.
Agenerase must not be administered concurrently with medicinal products with narrow therapeutic windows that are substrates of cytochrome P450 3A4 CYP3A4.
EVOTAZ must not be used in combination with medicinal products that are substrates of CYP3A4 and have a narrow therapeutic index.
Hence, clinically relevant drug-drug interactions are unlikely when apremilast is co-administered with drugs that are substrates or inhibitors of these transporters.
The inhibition of glucuronidation may cause interactions with medicinal products which are substrates of UGT1A1 and exclusively cleared by this pathway.
Lamivudine-TP and carbovir-TP(the active triphosphate form of abacavir) are substrates for and competitive inhibitors of HIV reverse transcriptase RT.
drugs that induce or are substrates of the CYP2B6 isozyme.
Therefore, caffeine has the potential to interact with active substances that are substrates for CYP1A2, inhibit CYP1A2,
Co-administration of Orkambi with medicinal products that are substrates for OAT1/3 and BCRP transport may increase plasma concentrations of such medicinal products.
Therefore, crizotinib may have the potential to increase plasma concentrations of coadministered medicinal products that are substrates of P-gp see section 4.5.
Coadministration of lapatinib with medicinal product with narrow therapeutic windows that are substrates of CYP3A4 or CYP2C8 should be avoided see section 4.5.