They were also treated to a special lecture by 2001 Nobel Laureate Tim Hunt, who discussed recent results of research on the mechanism of cell cycle regulation, a hot area of research in the field of chemical biology.
Yoshio Masui at Toronto University reported that the cell cycle duration is inversely proportional to the cell radius squared after the MBT in Xenopus embryo.
We have found a yeast mutant at gene SAH1 of S-adenosylhomocysteine(AdoHcy) hydrolase in the course of analyzing the cell cycle control mechanism using Ca2.
Eukaryotic DNA replication initiates from multiple sites, called replication origins, scattered throughout chromosomes and this initiation process is strictly regulated by the cell cycle.
It appears that the activity of the proteolytic machinery is finely tuned by proteins like Cdc29 and Cdh1 so that appropriate targets are degraded at the correct time during the cell cycle.
We found that salidroside considerably reversed senescence-like phenotypes in the oxidant challenged model, including alterations of morphology, cell cycle, SA-β-gal staining, DNA damage,
Because it seems better to consider habitable 24 hours as a day(1 turn around the rotation, 4 to 5 hours to 8 hours is early, the cell cycle is also strange)…?
Cell cycle studies, a field of biology that examines what happens inside a cell as it prepares to divide and reproduce, often uses a simple organism called fission yeast as a model, but it is usually cultivated in cultures containing over 100 mmol/L glucose, a concentration too high to make the data relevant to research into human metabolism.
This analysis is useful for study not only on the impact of microgravity or space radiation, but also into the relationship between the space environment and oxidative stress, cell cycle, and the dynamic state of various gene groups related to aging, life-span, and so on.
Ground-breaking programs with tremendous potential Kinases play a key role in regulating most cell functions, such as proliferation, cell cycle progression, metabolism, survival/apoptosis, repair of damaged DNA, motility and response to the micro-environment.
In the unstressed normal cells the p53 level is low and it is inactive. However with stress especially with DNA damage it is activated to promote arrest of cell cycle and repair of DNA damage or induction of apoptosis.
In particular, most of the reactions, which are initiated once and only once at a specific stage of the cell cycle(such as DNA replication and segregation), are triggered by the completion of the preceding reaction.
Through lectures on the cell cycle, development, and related fields of basic biology by researchers from Japan, Singapore, and Germany, this joint symposium set out to promote an international exchange of scientific ideas unhampered by boundaries of nation or field.
Radiobiology training aims to teach students the techniques for basic general experiments in radiobiology and to gain insights into the mechanisms behind DNA damage repair, changes in cell cycle, cell death and tissue damage due to radiation.
Unlike other cells that die in response to ionizing radiation, LCs can resist the effects of irradiation through their enhanced ability to rapidly repair DNA damage, due in part to their higher expression of the cell cycle? inhibitor CDKN1A p21.
In the cell cycle there are points of restriction that impede the normal continuation of the cycle for various reasons, such as, for example, if the cells have not attained sufficient size, lack nutrients, the DNA is damaged or receives outside chemical damage, etc.
We use the following experimental systems: in vitro culture systems using mouse and human cell lines in vitro differentiation systems using ES cells and primary cultures mouse model systems using knockout and transgenic mice Major Research Topics Cell cycle control and oncogenesis Cell cycle control and oncogenesis: During the cell cycle, whether cells should proliferate or stop growing and prepare for differentiation is decided at the G1 phase.
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