英語 での Acute lymphoblastic leukemia の使用例とその 日本語 への翻訳
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Philadelphia chromosome(Ph)/BCR/ABL-positive acute lymphoblastic leukemia is the most common genetic abnormality associated with adult acute lymphocytic leukemia and has been shown to confer the worst prognosis to both children and adults.
In a federally funded, randomized phase III clinical trial performed by the Children's Oncology Group(COG), 90% of children and young adults with T-cell acute lymphoblastic leukemia(T-ALL) or T-cell lymphoblastic lymphoma(T-LL) were alive four years after starting treatment regimens on this trial, and 84% were cancer free.
ALL= acute lymphoblastic leukemia;
Acute lymphoblastic leukemia detected.
ALL= acute lymphoblastic leukemia;
Undergoing HCT for acute lymphoblastic leukemia.
ALL= acute lymphoblastic leukemia; BFM= Berlin-Frankfurt-Münster;
The PDQ summary on Childhood Acute Lymphoblastic Leukemia Treatment.
Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia(CML) and certain forms of acute lymphoblastic leukemia(ALL).
In 2017, the FDA approved the first CAR T-cell therapies for children and young adults with a form of acute lymphoblastic leukemia(ALL), and then for adults with advanced lymphomas.
The development of Chimeric Antigen Receptor T-cell(CAR-T) treatment, CTL019: tisagenlecleucel, a cellular therapy consisting of autologous T cells transduced with an anti-CD19 chimeric antigen receptor for the patients with relapsed or refractory CD19 positive Acute Lymphoblastic Leukemia and Diffused Large B Cell Lymphoma.
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Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy.
Standard treatment options for newly diagnosed childhood acute lymphoblastic leukemia(ALL) include the following.