英語 での Epidermal growth factor receptor の使用例とその 日本語 への翻訳
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Patients with known EGFR(Epidermal growth factor receptor) tyrosine kinase(TK) activating mutations and anaplastic lymphoma kinase(ALK) rearrangements are not eligible for the study(prospective testing is not planned within this study).
Activation of EGFR(epidermal growth factor receptor) transactivated AXL, and this ligand-independent AXL activity diversified EGFR-induced signaling into additional downstream pathways beyond those triggered by EGFR alone.
Vectibix, a monoclonal antibody that binds to a protein called epidermal growth factor receptor or EGFR on some cancer cells, received an accelerated approval after showing effectiveness in slowing tumor growth and, in some cases, reducing the size of the tumor.
NSCLC is the most common type of lung cancer: activating epidermal growth factor receptor(EGFR) gene mutations are more frequently observed in non-smokers and women, and occur in 50% of Asians and only 10% of non-Asians.
He examines several well-studied receptors- the bacterial aspartate receptor(Tar), human epidermal growth factor receptor(EGFR), and human brain-derived neurotrophin receptor(BDNFR)- and comes to a conclusion that they all have similar chemical structures with or without their corresponding ligands.
The Oncotype DX assay report now includes quantitative scores for oestrogen receptor(ER), progesterone receptor(PR) and human epidermal growth factor receptor 2(HER2) gene expression by RT-PCR(all reports generated as of September 20, 2008).
These included 26 per cent of oestrogen receptor positive(ER+) and human epidermal growth factor receptor 2-negative(HER2-) tumours, which had a 42-55 per cent risk of recurrence up to 20 years after diagnosis.
This review cannot recommend which women might have more benefit from using tamoxifen in terms of age, menopausal status or type of DCIS oestrogen receptor(ER)-positive versus ER-negative or human epidermal growth factor receptor 2(HER2)-positive or HER2-negative DCIS.
Search results detail| Kusurino-Shiori(Drug information Sheet) This medicine suppresses the growth of breast cancer cells with high expression(overexpression) of HER2(human epidermal growth factor receptor 2) by selectively suppressing the function of a protein related to cancer cell growth called HER2. It is usually used to treat inoperable or recurrent breast cancer in which HER2 overexpression is confirmed.
Afatinib blocks proteins called epidermal growth factor receptors(EGFR).
In a phase II trial of cediranib, an inhibitor of all three known vascular epidermal growth factor receptors, 15 of 43 adult patients(35%) with metastatic alveolar soft part sarcoma had partial responses.
For further information as to human epidermal growth factor receptor 2(HER2) status, please refer to section 5.1.
For further information as to human epidermal growth factor receptor 2(HER2) status, referral to section 5.1 is suggested.
In contrast, while the EGFR(epidermal growth factor receptor) gene is frequently altered in HPV-negative tumors in smokers, it is rarely abnormal in HPV-positive tumors.
Drug type: Erlotinib is a targeted therapy, Erlotinib is classified as a epidermal growth factor receptor(EGFR) inhibitor- protein-tyrosine kinase inhibitor(for more detail, see"How this drug works," below.).
Thomas Baumert and colleagues now report that two receptor tyrosine kinases, epidermal growth factor receptor(EGFR) and ephrin receptor A2(EphA2), are cellular cofactors involved in entry of HCV into liver cells.
Around 10% to 15% of people with NSCLC will have a specific kind of cancer known as epidermal growth factor receptor positive(EGFR M+) in which there are specific changes to the cancer cells in the genes controlling tumour growth. .
Human epidermal growth factor receptor 2(HER2).
HER2= human epidermal growth factor receptor 2;
See human epidermal growth factor receptor 2.