KLINISK RELEVANT - oversættelse til Engelsk

• clinically relevant
• clinically meaningful
• medically relevant
• of clinical relevance
• clinical relevant

Eksempler på brug af Klinisk relevant på Dansk og deres oversættelser til Engelsk

Orlistat medfører ikke et klinisk relevant vægttab hos personer med BMI mindre end 28.
Orlistat does not induce a clinical relevant weight loss in patients with BMI below 28 kg/m2.

En klinisk relevant reduktion på 50% i biokemiske markører for knogleresorption blev observeret allerede en måned efter start på behandling med ibandronsyre 2, 5 mg.
A clinically meaningful reduction of 50% of biochemical markers of bone resorption was observed as early as one month after starting treatment with ibandronic acid 2.5 mg.

Alder har ingen klinisk relevant effekt på nicotinsyres(depotformulering) farmakokinetik på basis af en sammensat analyse af personer i alderen 18- 65 år.
Age has no clinically meaningful effect on pharmacokinetics of nicotinic acid(prolonged-release formulation) based on a composite analysis of subjects ages 18-65 years.

Når det er klinisk relevant, kan et direkte skift fra monoterapi til den faste kombination overvejes.
When clinically appropriate, direct change from monotherapy to the fixed-dose combination may be considered.

Race har ingen klinisk relevant effekt på nicotinsyres(depotformulering) farmakokinetik på basis af farmakokinetiske data,
Race has no clinically meaningful effect on the pharmacokinetics of nicotinic acid(prolonged-release formulation)

derefter når det er klinisk relevant.
thereafter as judged clinically appropriate.

Race har ingen klinisk relevant effekt på laropiprants farmakokinetik på basis af en sammensat analyse af farmakokinetiske data, herunder hvide, latinamerikanere,
Race had no clinically meaningful effect on the pharmacokinetics of laropiprant based on a composite analysis of pharmacokinetic data including subjects of White,

Patienter med mild nyreinsufficiens havde ikke en klinisk relevant stigning i plasmakoncentrationen af sitagliptin sammenlignet med de normale raske kontrolpersoner.
Patients with mild renal insufficiency did not have a clinically meaningful increase in the plasma concentration of sitagliptin as compared to normal healthy control subjects.

Alder havde ingen klinisk relevant indflydelse på sitagliptins farmakokinetik baseret på en farmakokinetisk populationsanalyse af fase I- og fase II- data.
Age did not have a clinically meaningful impact on the pharmacokinetics of sitagliptin based on a population pharmacokinetic analysis of Phase I and Phase II data.

Ketoconazol- Den stærke CYP3A4/ 5- inhibitor ketoconazol øger den systemiske eksponering for lasofoxifen med 20%, hvilket ikke vurderes at være klinisk relevant.
Ketoconazole- The strong CYP3A4/ 5 inhibitor ketoconazole increased the systemic exposure of lasofoxifene by 20% which is not considered to be clinically meaningful.

Paroxetin- Den stærke CYP2D6- inhibitor paroxetin øger den systemiske eksponering for lasofoxifen med 35%, hvilket ikke vurderes at være klinisk relevant.
Paroxetine- The strong CYP2D6 inhibitor paroxetine increased the systemic exposure of lasofoxifene by 35% which is not considered to be clinically meaningful.

P- gp) havde ingen klinisk relevant indvirkning på laropiprants farmakokinetik.
did not have a clinically meaningful effect on the pharmacokinetics of laropiprant.

Administration af laropiprant 40 mg til ikke- dialyserede patienter med svær nyreinsufficiens resulterede ikke i klinisk relevant forandring i laropiprants AUC
Administration of laropiprant 40 mg in non-dialysed patients with severe renal insufficiency resulted in no clinically meaningful change in the AUC

En klinisk relevant påvirkning af raloxifen- plasmakoncentrationer ved samtidig administration af disse lægemidler blev ikke observeret.
No clinically relevant effects of the co-administration of the agents on raloxifene plasma concentrations were identified.

eller hvis der opstår klinisk relevant nedsat lungefunktion,
or there is a clinically relevant reduction in pulmonary function,

Galantamin og donepezil viser ikke klinisk relevant effekt på risperidons farmakokinetik
Galantamine and donepezil do not show a clinically relevant effect on the pharmacokinetics of risperidone

Trods en klinisk relevant reduktion i HbA1c sammenlignet med placebo,
In spite of a clinically relevant reduction in HbA1c compared to placebo,

Sammenlignet med placebo giver kombinationen en klinisk relevant forbedring af lungefunktion
When compared with placebo, the combination shows a clinically relevant improvement of lung function

Race Der er ikke noget der tyder på en klinisk relevant inter- etnisk forskel i tilstedeværelsen af ibandronsyre mellem asiater og kaukasere.
Race There is no evidence for clinically relevant interethnic differences between Asians and Caucasians in ibandronic acid disposition.

Analyser af plasmakoncentrationsdata fra patienter i kliniske studier tyder på, at enfuvirtids clearance ikke påvirkes klinisk relevant hos patienter med mild til moderat nyreinsufficiens.
Analysis of plasma concentration data from patients in clinical trials indicated that the clearance of enfuvirtide is not affected to any clinically relevant extent in patients with mild to moderate renal impairment.