DOSE REDUCTIONS - prijevod na Hrvatskom

• smanjenja doze
• smanjiti dozu
• smanjivati dozu
• smanjivanje doze
• sniženja doze
• snižavanje doze
• smanjenje doze
• smanjenjem doze

Primjeri korištenja Dose reductions na Engleski i njihovi prijevodi na Hrvatskom

safety data, dose reductions are recommended in the elder groups:
podataka o sigurnosti preporučuju se smanjenja doze kod starijih skupina: bolesnika u dobi

Dose interruptions and/or dose reductions may be required based on individual safety and tolerability.
Prekidi primjene i/ili smanjenja doze mogu biti potrebni ovisno o sigurnosti i podnošljivosti lijeka u pojedinog bolesnika.

In the once every three weeks group, 72% of patients required dose reductions.
U skupini koja je dobivala Aranesp jednom u 3 tjedna kod 72% bolesnika bilo je potrebno smanjiti dozu.

pharmacokinetic properties of TMZ, it is unlikely that dose reductions are required in patients with severe hepatic impairment
vjerojatno neće biti potrebno smanjivati dozu u bolesnika s teškim oštećenjem funkcije jetre

Dose reductions are permitted to a minimum dose of 20 mg/m2/dose twice daily.
Smanjenja doze su dozvoljena do minimalne doze od 20 mg/m2/dozi primjenjeno dva puta dnevno.

The starting dose of 175 mg was associated with a significant incidence of adverse events and required dose reductions/delays in the majority of patients.
Početna doza od 175 mg bila je povezana sa značajnom incidencijom štetnih događaja pa je u većine bolesnika bilo potrebno smanjiti dozu ili odgoditi primjenu.

Dose reductions for subsequent cycles are based on nadir ANC, platelet count
Smanjenja doze u sljedećim ciklusima temelje se na najnižim vrijednostima apsolutnog broja neutrofila

Dose reductions should be considered if the platelet count decreases below 100,000/mm3,
Treba razmotriti smanjivanje doze ako se razina trombocita snizi na manje od 100 000/mm3,

patients should be monitored and appropriate dose reductions of Pegasys during the course of therapy should be made in the event of adverse reactions.
početnu dozu odnosno stupanj oštećenja bubrega, ove bolesnike treba nadzirati te u slučaju nuspojava prikladno smanjivati dozu lijeka Pegasys.

A: Further dose reductions should be considered on an individual patient basis as limited data are available for doses below 10 mg.
Daljnja sniženja doze treba razmotriti u svakog bolesnika pojedinačno jer su dostupni podaci za doze niže od 10 mg ograničeni.

Dose reductions or discontinuation for increased serum transaminases and total bilirubin are
Smanjenja doze ili prekid liječenja zbog povišenih vrijednosti serumskih transaminaza

In PV, dose reductions should also be considered if haemoglobin decreases below 12 g/dl and is recommended if it decreases below 10 g/dl.
Kod PV-a, smanjivanje doze treba razmotriti i ako se hemoglobin smanji ispod 12 g/dl te se preporučuje ako se smanji ispod 10 g/dl.

Adverse reactions that most commonly led to dose reductions(in≥5% of patients)
Nuspojave koje su najčešće dovele do sniženja doze(u ≥5% bolesnika)

Dose reductions or discontinuation of treatment with pasireotide due to hyperglycaemia were infrequent in clinical studies with pasireotide.
Smanjenja doze ili prekidi terapije pasireotidom zbog hiperglikemije nisu bili učestali u kliničkim ispitivanjima s pasireotidom.

Dose reductions or discontinuation of the drug may be necessary for clinically significant increases in potassium.
Smanjenje doze ili prekid lijeka može biti neophodno za klinički značajna povećanja kalijuma.

If adverse reactions occur after dose reductions to 1 mg, then the medicinal product should be discontinued.
Ako nuspojave nastupe nakon smanjenja doze na 1 mg, onda je potrebno prekinuti primjenu lijeka.

Dose reductions and discontinuations during the monotherapy phase should be applied according to Tables 2 and 3.
Smanjenje doze i prekid davanja lijeka tijekom faze monoterapije treba provesti sukladno napucima u Tablicama 2 i 3.

Dose reductions were noted to slow or stop the progression of splenic enlargement and in 3% of patients a splenectomy was required.
Pokazalo se da se povećavanje slezene usporava ili zaustavlja smanjenjem doze, a u 3% bolesnika morala se obaviti splenektomija.

If recurrence after irinotecan and 5-FU dose reductions, reduction of ZALTRAP dose to 2 mg/kg could be considered.
Ako se ponovno javi nakon smanjenja doze irinotekana i 5-FU, treba razmotriti smanjenje doze lijeka ZALTRAP na 2 mg/kg.

Dose reductions and dose interruptions occurred in 79%
Smanjenje doze i prekidi doza su se javili u 79%,