Exemple de utilizare a Is a substrate în Engleză și traducerile lor în Română
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Additionally, in vitro studies have shown that saquinavir is a substrate and an inhibitor for P-glycoprotein(P-gp).
When efavirenz is co-administered with an anticonvulsant that is a substrate of CYP450 isoenzymes,
When Atripla is co- administered with an anticonvulsant that is a substrate of CYP isozymes, periodic monitoring of anticonvulsant levels should be conducted.
Additionally, in vitro studies have shown that saquinavir is a substrate and an inhibitor for P-glycoprotein(P-gp).
When Atripla is co- administered with an anticonvulsant that is a substrate of CYP450 isoenzymes, periodic monitoring of anticonvulsant levels should be conducted.
In vitro experiments with human Caco-2 cells indicated that simeprevir is a substrate of P-gp.
Posaconazole is metabolised via UDP glucuronidation(phase 2 enzymes) and is a substrate for p- glycoprotein(P-gp) efflux in vitro.
the active metabolite is a substrate for, or an inhibitor of, the major cytochrome P450 isoforms.
osimertinib is a substrate of P-glycoprotein and breast cancer resistant protein(BCRP),
In addition, M1 is a substrate of the hepatic uptake transporters OATP family
When efavirenz is co- administered with a calcium channel blocker that is a substrate of the CYP3A4 enzyme,
In vitro, DM1 was a substrate of P-glycoprotein(P-gp).
Consistent with apremilast being a substrate of CYP3A4, apremilast exposure is decreased when administered concomitantly with rifampicin,
Tipiracil hydrochloride was a substrate for OCT2 and MATE1,
In vitro, MMAE was a substrate of P-gp and was not an inhibitor of P-gp at clinical concentrations.
inhibitors: Preclinical studies indicate that aliskiren might be a substrate of organic anion transporting polypeptides.
Preclinical studies indicate that aliskiren might be a substrate of organic anion transporting polypeptides.
induce or are a substrate for one of the CYP isozymes
What is a substrate?
Fidaxomicin is a substrate of P-gp.