Examples of using Is a substrate in English and their translations into Slovak
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Medicine
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Programming
When efavirenz is co-administered with a calcium channel blocker that is a substrate of the CYP3A4 enzyme,
Posaconazole is metabolised via UDP glucuronidation(phase 2 enzymes) and is a substrate for p- glycoprotein(P-gp) efflux in vitro.
In vitro studies showed that umeclidinium bromide is principally metabolised by cytochrome P450 2D6(CYP2D6) and is a substrate for the P-glycoprotein(P-gp) transporter.
In vitro studies showed that umeclidinium is primarily metabolised by cytochrome P450 2D6(CYP2D6) and is a substrate for the P-glycoprotein(P-gp) transporter.
In vitro studies showed that vilanterol is primarily metabolised by cytochrome P450 3A4(CYP3A4) and is a substrate for the P-gp transporter.
Posaconazole is metabolised via UDP glucuronidation(phase 2 enzymes) and is a substrate for p- glycoprotein(P-gp) efflux in vitro.
the active metabolite is a substrate for, or an inhibitor of, the major cytochrome P450 isoforms.
The results of investigations in vitro with human liver tissue showed that valsartan is a substrate for hepatic transporter OATP1B1
The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1
Sofosbuvir is a substrate of drug transporter P-gp
Sofosbuvir is a substrate for The p-glycoprotein Transporter drug
guanfacine is a substrate of OCT1 and OCT2,
Edoxaban is a substrate for the efflux transporter P-glycoprotein(P- gp),
In vitro studies indicated that eluxadoline is a substrate and an inhibitor of the hepatic uptake transporter OATP1B1; a substrate for the hepatic efflux transporter MRP2 and is not a substrate or inhibitor of the P-gp and BCRP transporters.
due to which it can be a substrate.
Preclinical studies indicate that aliskiren might be a substrate of organic anion transporting polypeptides.
Consistent with apremilast being a substrate of CYP3A4, apremilast exposure is decreased when administered concomitantly with rifampicin, a strong inducer of CYP3A4.
Tipiracil hydrochloride was a substrate for OCT2 and MATE1,
Preclinical studies indicate that aliskiren might be a substrate of organic anion transporting polypeptides.
induce or are a substrate for one of the CYP isozymes