Examples of using Pgp in English and their translations into Greek
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Financial
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Official/political
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Computer
Known and theoretical interactions with selected inhibitors and inducers of CYP3A4 and PgP are listed in Table 2 below.
Everolimus trough concentrations should be assessed at least 1 week after the addition of a moderate CYP3A4 or PgP inhibitor.
Use caution when co-administration of moderate CYP3A4 inhibitors or PgP inhibitors cannot be avoided.
In clinical pharmacology studies there were no clinically meaningful effects on exposure when baricitinib was coadministered with digoxin(Pgp substrate) or methotrexate(substrate of several transporters).
medicinal products that inhibit Pgp may increase tipranavir plasma concentrations.
Concomitant administration of inhibitors of Pgp, e.g. cyclosporine
Tacrolimus has been found in vitro to have a similar level of inhibitory effect on Pgp as that seen with itraconazole and cyclosporine.
Selection of an alternate concomitant medicinal product with no or minimal Pgp induction potential should be considered.
Finally the MAH was also requested to update this section with more information concerning the inhibitory potential of ciclosporin on other transporters than Pgp.
CYP3A4 and PgP inhibitors increasing everolimus concentrations Substances that are inhibitors of CYP3A4 or PgP may increase everolimus blood concentrations by decreasing metabolism
CYP3A4 and PgP inducers decreasing everolimus concentrations Substances that are inducers of CYP3A4 or PgP may decrease everolimus blood concentrations by increasing metabolism
Data suggest that, although ritonavir is a Pgp inhibitor, the net effect of APTIVUS, co-administered with low dose ritonavir, at the proposed dose regimen at steady-state, is Pgp induction.
agents that induce CYP3A and/ or Pgp may decrease tipranavir concentrations
an inhibitor of Pgp and a strong inhibitor of CYP3A4,
PGP is unlikely to cause early labor.
PGP can be used to send messages confidentially.
To download PGP, you can rely on these trusted sites.
PGP and GNUPG signatures
A very popular method called PGP(pretty good privacy).
Error running PGP.