Examples of using Integrase in English and their translations into Italian
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Medicine
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Ecclesiastic
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Ecclesiastic
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Computer
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Official/political
dolutegravir belongs to a group of anti-retroviral medicines called integrase inhibitors INIs.
resistance to integrase inhibitors, the use of Triumeq is not recommended for patients with integrase inhibitor resistance.
previously treated patients, including those with resistance to integrase inhibitors.
suspected to be resistant to integrase inhibitors; in these patients, giving Tivicay with medicines that decrease its effectiveness should be avoided.
protease and integrase.
PK/PD modelling using pooled data from clinical studies in integrase resistant patients suggest that increasing the dose from 50 mg twice daily to 100 mg twice daily may increase the effectiveness of dolutegravir in patients with integrase resistance and limited treatment options due to advanced multi class resistance.
When mutations listed as secondary integrase inhibitor associated mutations(for raltegravir/elvitegravir) are added to
The second study in previously treated patients involved 183 patients with infection resistant to previous treatment that had involved an integrase inhibitor(i.e. their infection was resistant to several classes of medicine, including previous integrase inhibitors): adding Tivicay twice daily to other treatment resulted in a response rate of 69% after 24 weeks of therapy.
Integrase is an HIV-1 encoded enzyme that is required for viral replication.
The virus produces an enzyme called HIV integrase.
How ISENTRESS works The virus produces an enzyme called HIV integrase.
The HIV virus produces an enzyme called HIV integrase.
Integrase inhibitors prevent HIV DNA from being integrated into human DNA.
No participants developed integrase inhibitor resistance.
Dolutegravir belongs to a group of anti-retroviral medicines called integrase inhibitors INIs.
In the presence of integrase class resistance alternative combinations that do not include fosamprenavir/ritonavir should be considered.
In the presence of integrase class resistance this combination should be avoided see section 4.4.
Integrase is a viral enzyme that integrates retroviral DNA into the host cell genome.
No dose adjustment is necessary in the absence of integrase class resistance.
These increases may be clinically relevant in the presence of certain integrase class resistance.