Examples of using Trough levels in English and their translations into Norwegian
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increase the dose and aim for higher trough levels.
Blood trough levels of tacrolimus should also be closely monitored following conversion from tacrolimus products,
In clinical practice, whole blood trough levels have generally been in the range of 5-20 ng/mL in kidney transplant patients in the early post- transplant period, and 5-15 ng/mL during subsequent maintenance therapy.
monitoring should be performed every 5 to 7 days until 3 consecutive trough levels have shown stable concentrations of sirolimus after dose adjustment or after loading dose due to the delay in reaching steady-state because of the prolonged half-life.
Blood trough levels of tacrolimus should also be closely monitored following conversion from Prograf to Advagraf,
In PNH patients, pharmacodynamic activity correlates directly with eculizumab serum concentrations and maintenance of trough levels above 35 microgram/ml results in essentially complete blockade of haemolytic activity in the majority of PNH patients.
from Advagraf prolonged-release capsules to Envarsus, trough levels should be measured prior to conversion and within two weeks after conversion.
Data from the clinical trials of HyQvia show that serum IgG trough levels can be maintained by dosing regimens of 320 to 1,000 mg/kg body weight/4 weeks given at intervals of 3- or 4-weeks.
In UC patients treated with 50 mg or 100 mg golimumab subcutaneously every 4 weeks, concomitant use of immunomodulators did not have a substantial effect on steady-state trough levels of golimumab.
Careful and frequent monitoring of tacrolimus trough levels is recommended in the first 2 weeks post-transplant to ensure adequate exposure to the active substance in the immediate post-transplant period.
The steady-state trough ustekinumab levels resulting from 90 mg ustekinumab every 8 weeks were associated with higher clinical remission rates as compared to the steady-state trough levels following 90 mg every 12 weeks.
Blood trough levels of tacrolimus should also be closely monitored when clinical signs of toxicity
lower initial tacrolimus doses with target trough levels of 10 to 15 ng/ml, and most recently allograft
The dose regimen should achieve a trough level of IgG(measured before the next infusion)
The dose required to achieve a trough level of 5- 6 g/l is of the order of 0.2- 0.8 g/kg/month.
The dose required to achieve a trough level of 6 g/l is of the order of 0.4-0.8 g/kg body weight per month.
checking the trough level and assessing tolerability before increasing the dose.
The dose required to achieve a trough level of 5-6 g/l is of the order of 0.2-0.8 g/kg/month.
Long-term efficacy appears to be most likely in patients whose nevirapine trough levels exceed 3.5 µg/ml.
subcutaneous injections of Zutectra per week or fortnightly according to serum anti-HBs trough levels.