Examples of using Factor xa in English and their translations into Romanian
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they act directly on the coagulation factor Xa, consequently hindering the transformation of prothrombin I into thrombin(factor IIa).
Apixaban also demonstrates anti-FXa activity as evident by reduction in Factor Xa enzyme activity in multiple commercial anti-FXa kits,
The anticoagulants, direct inhibitors of factor Xa, bind in a highly selective manner to its active site,
several PD endpoints(Factor Xa inhibition, PT,
In vitro purified enoxaparin has a high anti factor Xa blood clotting(anti-Xa)(approximately 100 IU/mg)
By blocking factor Xa, the medicine reduces the levels of thrombin in the blood,
a non-phospholipid dependent coagulation test such as a Factor Xa(chromogenic) assay or an alternative anticoagulant not requiring aPTT monitoring may be considered.
Certain anticoagulants including those blocking a blood clotting factor( factor Xa) should not be used in patients with factor X deficiency receiving Coagadex due to a risk of blood clots.
In patients, baseline factor Xa and PT were influenced by the surgery resulting in a difference in the concentration-PT slope between the day post- surgery
or direct Factor Xa inhibitors(e.g., rivaroxaban and apixaban).
Arg506 diminish the molecule's attraction to Factor Xa, and though the first of these sites is slow to be cleaved, it is entirely necessary to the functioning of Factor V. Protein S aids this process by catalysing the proteolysis at Arg306, in which the A2 domain of Factor V is dissociated from the rest of the protein.[35] Protein S also binds to Factor Xa, inhibiting the latter from diminishing APC's inactivation of Factor Va.[16]: 2386.
by enhancing the inhibitory action against coagulation factors Xa and IIa(thrombin).
binding speed of antithrombin III itself with factors Xa and IIa.
Dose-dependent inhibition of factor Xa activity was observed in humans.
Enzymes Direct thrombin inhibitors Direct factor xa inhibitors.
is a‘factor Xa inhibitor'.
is a‘factor Xa inhibitor'.
Pharmacodynamic effects Dose-dependent inhibition of Factor Xa activity was observed in humans.
Activity of factor Xa, which is an important component of blood clotting.