Examples of using Cmax in English and their translations into Slovak
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less than dose-proportional for Cmax for doses exceeding 50 mg.
Obese men when applying Nikvitina marked significantly lower rates of AUC and Cmax compared to those of men with normal body weight.
Respectively; the AUC of the active metabolite of ulipristal acetate increased 1.5 fold while the Cmax of the active metabolite decreased(0.52 fold change).
A single dose administration of digoxin 1 mg with liraglutide resulted in a reduction of digoxin AUC by 16%; Cmax decreased by 31%.
A single dose administration of lisinopril 20 mg with liraglutide resulted in a reduction of lisinopril AUC by 15%; Cmax decreased by 27%.
In a small pharmacokinetic study, the Cmax and AUC of prucalopride were, on average, 10-20% higher in patients with
Omeprazole, given in doses of 40 mg to healthy subjects in a cross-over study, increased Cmax and AUC for cilostazol by 18%
The steady-state Cmax value of ceritinib at the recommended clinical dose of 750 mg daily may exceed the Ki values for CYP3A
increased the repaglinide AUC 8.1-fold and Cmax 2.4-fold in healthy volunteers.
but decreased the Cmax by 34% to 46%.
Following administration of a supratherapeutic dose of 10 mg linagliptin concomitantly with 40 mg of simvastatin daily for 6 days, the plasma AUC of simvastatin was increased by 34%, and the plasma Cmax by 10%.
2-fold and Cmax by 15%, relative to the AUC and Cmax values for tadalafil alone.
In a study in patients with type 2 diabetes mellitus after subcutaneous administration of 0.2 Units/kg insulin glulisine, the Cmax was 91 µUnits/ml with the interquartile range from 78 to 104 µUnits/ml.
had no impact on Cmax.
severe hepatic impairment, AUCinf was increased 60% and 79%, Cmax was increased 67%
2-fold and Cmax by 15%, relative to the AUC and Cmax values for tadalafil alone.
nateglinide showed linear pharmacokinetics for both AUC and Cmax, and tmax was independent of dose.
did not alter dabrafenib Cmax relative to administration of dabrafenib 75 mg twice daily alone.
a 33% increase in dabrafenib Cmax relative to administration of dabrafenib 75 mg twice daily alone.
Atorvastatin concentrations in the blood plasma are higher(about 40% for Cmax and 30% for AUC)