英語 での Tumor suppressor の使用例とその 日本語 への翻訳
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This finding suggests that loss of function of the fumarate hydratase protein is the basis for tumor formation in HLRCC and supports a tumor suppressor function for FH.[2][4].
Eucommia Extract can be used antihypertensive, anti-tumor, chlorogenic acid has the effects of anti-cancer and tumor suppressor, anti-aging, against free radicals, promoting metabolism, and it also has other functions: diuretic, gallbladder, blood fat, fetus protection.
The range of mutations reported for osteosarcoma tumors at diagnosis do not provide obvious therapeutic targets, as they primarily reflect loss of tumor suppressor genes(e.g., TP53, RB1, PTEN) rather than activation of targetable oncogenes.
In the second study, ALK mutations were not observed in either diagnostic or relapse specimens, but relapse-specific recurrent single-nucleotide variants were observed in 11 genes, including the putative CHD5 neuroblastoma tumor suppressor gene located at chromosome 1p36.
In the second study, ALK mutations were not observed in either diagnostic or relapse specimens, but relapse-specific recurrent single-nucleotide variants were observed in 11 genes, including the putative CHD5 neuroblastoma tumor suppressor gene located at chromosome 1p36.[22].
In most breast and ovarian cancers that have been studied from carriers of pathogenic variants, deletion of the normal allele results in loss of all function, leading to the classification of BRCA1 and BRCA2 as tumor suppressor genes.
Tsuchiya graduate students to study the role of the p53 tumor suppressor gene in brain tumors, apoptosis in the brain are thin Glioblastoma relationship with radiosensitivity, suggesting that strongly involved in the irreversible arrest stage G0.
BOTH the Genome and the Epigenome send signals out to our cancer promoting oncogenes(which we refer to as our“enemy”), and to our tumor suppressor and DNA repair genes(referred to as our“friends”).
Of tumor suppressor proteins.
Cancer(tumor suppressor).
Tumor suppressor gene Rb.
TP53(tumor suppressor gene).
Tumor suppressor gene/protein expression.
Anti-tumor effects anti-cancer and tumor suppressor;
This protein may function as a tumor suppressor.
Like BRCA1, BRCA2 appears to behave like a tumor suppressor gene.
Now, TP53 is the most important tumor suppressor gene.
The tumor suppressor protein p53 is an attractive target for drug developers.
Development of a tumor suppressor gene screening method using the mouse transposon.