Primjeri korištenja Cmax na Engleski i njihovi prijevodi na Hrvatskom
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Administration with a high-fat meal decreased dapagliflozin Cmax by up to 50% and prolonged Tmax by approximately 1 hour, but did not alter AUC as compared with the fasted state.
After administering a single dose of Vantobra 170 mg to healthy volunteers Cmax of 1.1+ 0.4 µg/ml were reached after a tmax of approximately 4 hours.
Cmax and AUC were increased following either a high-fat meal(77% and 58%,
Corresponding steady-state mean Cmax, AUCtau, and Ctrough(mean± SD) were 1.1± 0.40 µg/mL,
For elvitegravir, Cmax and AUC increased 22% and 36% with a light meal,
For elvitegravir, Cmax and AUC increased 22% and 36% with a light meal,
For metformin, AUC decreased by 12% and Cmax decreased by 26% compared to fasting conditions.
Gender differences in plasma concentrations were observed, Cmax and AUC being approximately 3-and 2-fold higher, respectively, in females compared to males.
In the presence of digoxin, the Cmax and AUC of ticagrelor and its active metabolite were not affected.
Mean ospemifene Cmax and AUC0-24hr were 785 ng/mL
Mean ruxolitinib Cmax and total exposure(AUC)
No food effect is expected on Cmax, Tmax and AUC values following CIPII administration.
The Cmax and AUC following a 2- to 10-minute intravenous infusion of 27 mg/m2 was 4,232 ng/mL
The mean estimated vorapaxar Cmax and AUC were 35% and 33% higher, respectively, in patients with a body weight of<
The sachet formulation has a slightly higher Cmax than the capsules and thus the formulations are not bioequivalent.
therefore the peak concentrations Cmax.
After multipledoses of ticagrelor 90 mg b.i.d. the increase of dabigatran exposure is 1.56-fold and 1.46-fold(+56% and 46%) for Cmax and AUC, respectively.
As expected, empagliflozin 5 mg administered twice daily compared with 10 mg empagliflozin once daily resulted in lower Cmax and higher trough plasma empagliflozin concentrations Cmin.
At 24 hours, the plasma levels of vardenafil had fallen to approximately 4% of the maximum vardenafil plasma level Cmax.
Co-administration of a 300 mg tablet with a high fat breakfast reduced maraviroc Cmax and AUC by 33% in healthy volunteers.