GLAVNO ISPITIVANJE in English translation

• main study
• pivotal study
• main interrogation

Examples of using Glavno ispitivanje in Croatian and their translations into English

Glavno ispitivanje lijeka Vectibix u kombinaciji s„FOLFOX” kemoterapijskim protokolom obuhvatilo je 1183 bolesnika koji prethodno nisu primili terapiju za metastatki rak,
Vectibix in combination with FOLFOX has been investigated in a main study involving 1,183 patients who had not been treated before for their metastatic cancer,

Nadalje, provedeno je jedno glavno ispitivanje kako bi se ispitala sigurna primjena
In addition, one main study was carried out to examine the safety

Drugo glavno ispitivanje pokazalo je da dvije doze cjepivaCervarix koje su dane s razmakom od 5 do 13 mjeseci nisu bile manje djelotvorne u djevojaka od 9 do 14 godina od standardnog cijepljenja u tri doze u starijih osoba: sve prethodno nezaštićene osobe razvile su visoke razine zaštitnih protutijela protiv tipova virusa 16 i 18 mjesec dana nakon zadnje doze.
The second main study showed that two doses of Cervarix given 5 to 13 months apart were no less effective in girls aged 9 to 14 than a standard three-dose vaccination was in older subjects: all previously unprotected subjects had developed high levels of protective antibodies against virus types 16 and 18 one month after their last dose.

Bolesnici s blagim do umjerenim oštećenjem funkcije bubrega bili su uključeni u glavna ispitivanja.
Patients with mild and moderate renal impairment were included in the pivotal studies.

Lijek Zalmoxis ispitivan je u okviru jednog glavnog ispitivanja koje je uključivalo 30 bolesnika koji su bili podvrgnuti HSCT-u zbog ozbiljnog raka krvi.
Zalmoxis has been investigated in a main study involving 30 patients who had haploidentical HSCT for serious blood cancers.

Nakon dovršetka glavnog ispitivanja bolesnici su imali mogućnost primanja lijeka Deltyba tijekom 6 mjeseci u produžetku ispitivanja..
After the main study had finished, patients had the option to receive treatment with Deltyba for 6 months in an extension study..

Lijek Cabometyx ispitivan je u okviru jednog glavnog ispitivanja provedenog na 658 odraslih osoba s uznapredovalim karcinomom bubrežnih stanica koji se pogoršao unatoč liječenju inhibitorom VEGF-a.
Cabometyx has been investigated in one main study involving 658 adults with advanced renal cell carcinoma that had got worse despite treatment with a VEGF inhibitor.

Podaci glavnog ispitivanja pokazuju da Lartruvo u kombinaciji s doksorubicinom poboljšava preživljenje bez napredovanja bolesti
Data from the main study show that Lartruvo in combination with doxorubicin improves progression- free

Vpriv je u okviru jednoga glavnog ispitivanja, u kojem je sudjelovalo 35 bolesnika(uključujući devetero djece) s Gaucherovom bolesti tipa 1,
In one main study involving 35 patients(including 9 children) with type 1 Gaucher disease,

Lijek Onivyde ispitivan je u okviru jednog glavnog ispitivanja koje je obuhvatilo 417 bolesnika s metastatskim adenokarcinomom gušterače čija se bolest pogoršala unatoč terapiji gemcitabinom.
Onivyde was investigated in one main study involving 417 patients with metastatic adenocarcinoma of the pancreas whose cancer got worse despite cancer treatment that contained gemcitabine.

Rezultati glavnog ispitivanja pokazuju da lijek Strimvelis učinkovito djeluje na povećanje stope preživljavanja bolesnika koji boluju od bolesti ADA- SCID.
Results from the main study show that Strimvelis is effective at improving survival of ADA-SCID patients.

Ryzodeg je ispitivan u okviru glavnog ispitivanja na 584 odrasle osobe sa šećernom bolesti tipa 1
Ryzodeg has been studied in one main study involving 548 adults with type 1 diabetes

Thalidomide Celgene ispitivan je u sklopu jednog glavnog ispitivanja u kojemu je sudjelovalo 447 bolesnika s multiplim mijelomom.
Thalidomide Celgene was studied in one main study involving 447 patients with multiple myeloma.

Glavnim ispitivanjem lijeka Elaprase bilo je obuhvaćeno 96 bolesnih muškaraca u dobi od pet do 31 godine,
The main study of Elaprase involved 96 male patients aged between 5 and 31 years,

U bolesnika s kroničnim preopterećenjem željezom zbog transfuzija krvi lijek Exjade ispitivan je u okviru jednoga glavnog ispitivanja u kojemu je lijek Exjade uspoređivan s deferoksaminom na 591 bolesniku s beta-talasemijom major.
In chronic iron overload due to blood transfusions, Exjade was investigated in one main study comparing Exjade with deferoxamine in 591 patients with beta thalassaemia major.

Wakix je ispitivan u okviru dvaju glavnih ispitivanja koja su uključivala ukupno 261 odraslu osobu s narkolepsijom,
Wakix has been investigated in 2 main studies involving a total of 261 adults with narcolepsy,

Enbrel se ispitivao u pet glavnih ispitivanja u reumatoidnom artritisu, koje je obuhvatilo otprilike 2.2 bolesnika
Enbrel has been studied in five main studies in rheumatoid arthritis, involving about 2,200 patients

U slučaju ulcerativnog kolitisa, u dvama glavnim ispitivanjima lijek Simponi uspoređen je s placebom kod bolesnika koji nisu odgovorili na terapiju ili nisu mogli koristiti druge terapije.
For ulcerative colitis, Simponi was compared with placebo in two main studies in patients who had not responded to or could not use other treatments.

Galafold je istraživan u dvama glavnim ispitivanjima u kojima je sudjelovalo ukupno 127 bolesnika s Fabryjevom bolešću.
Galafold has been investigated in two main studies involving a total of 127 patients with Fabry disease.

Harvoni je ispitan u trima glavnim ispitivanjima koja su obuhvatila oko 2 000 bolesnika zaraženih hepatitisom C genotipa 1 kod kojih nije bilo prisutno zatajenje funkcije jetre.
Harvoni was investigated in three main studies involving a total of around 2,000 patients infected with hepatitis C of genotype 1 who did not have failure of liver function.