IN VITRO- FORSØG in English translation

• in vitro studies
• in vitro experiments
• in vitro studies in

Examples of using In vitro- forsøg in Danish and their translations into English

Metabolisme In vitro- forsøg med humane levermikrosomer indikerer,
Metabolism In vitro experiments with human liver microsomes(HLMs)

In vitro- forsøg med humane levermikrosomer har vist, at paliperidon ikke væsentligt hæmmer metaboliseringen af lægemidler, som metaboliseres af cytokrom P450- isozymer,
In vitro studies in human liver microsomes showed that paliperidone does not substantially inhibit the metabolism of medicines metabolised by cytochrome P450 isozymes,

baseret på resultaterne af in vitro- forsøg, hvor adefovir ikke havde nogen indflydelse på de almindelige CYP- isoformer, som vides at være involveret i human lægemiddelstofskifte,
based on the results of in vitro experiments in which adefovir did not influence any of the common CYP isoforms known to be involved in human drug metabolism

På baggrund af in vitro- forsøg forventes det ikke, at doripenem inhiberer eller inducerer aktiviteterne af CYP450.
Based on in vitro studies it is not expected that doripenem will inhibit or induce the activities of CYP450.

In vitro- forsøg tyder også på, at polymorfiske enzymer som CYP2C9,
In vitro studies also indicate that polymorphic enzymes CYP2C9,

Baseret på in vitro- forsøg er CYP3A4 og CYP2D6 ansvarlige for dehydrogenering
Based on in vitro studies, CYP3A4 and CYP2D6 enzymes are responsible for dehydrogenation

In vitro- forsøg tyder på, at der er usandsynligt, at vareniclin ændrer farmakokinetikken for stoffer, der primært metaboliseres af cytochrom P450- enzymer.
In vitro studies indicate that varenicline is unlikely to alter the pharmacokinetics of compounds that are primarily metabolised by cytochrome P450 enzymes.

In vitro- forsøg har vist, at clofarabin hæmmer cellevækst i
In vitro studies have demonstrated that clofarabine inhibits cell growth in

Metabolisme og udskillelse In vitro- forsøg tyder på, at lenalidomid ikke har nogen hæmmende virkning på CYP1A2,
Metabolism and excretion In vitro studies indicate that lenalidomide has no inhibitory effect on CYP1 A2,

In vitro- forsøg med menneskelige levermikrosomer eller primære hepatocytter viser,
In vitro studies using human liver microsomes

In vitro- forsøg med dexrazoxan ved test i humane mikrosomer har vist høj stabilitet ved dexrazoxan, hvilket indikerer, at væsentlig metabolisme via cytokrom P450 er usandsynlig.
In vitro studies on dexrazoxane when tested in human microsomes have shown high stability of dexrazoxane indicating that major metabolism via cytochrome P450 is unlikely.

Metabolisme In vitro- forsøg har vist,
Metabolism In vitro studies have demonstrated that there is no

Resultaterne af in vitro- forsøg med humane levermikrosomer tyder på, at pemetrexed ikke burde forårsage en klinisk signifikant inhibition af den metaboliske clearance af lægemidler, der metaboliseres af CYP3A, CYP2D6, CYP2C9 og CYP1A2.
Results from in vitro studies with human liver microsomes indicated that pemetrexed would not be predicted to cause clinically significant inhibition of the metabolic clearance of drugs metabolised by CYP3A, CYP2D6, CYP2C9, and CYP1A2.

In vitro- forsøg har vist, at methylnaltrexon er en my- opioidreceptorantagonist(inhibitionskonstant[Ki] 28 nM) med 8- fold
In vitro studies have shown methylnaltrexone to be a mu-opioid receptor antagonist(inhibition constant[Ki]

Forsøg med mennesker og in vitro- forsøg, hvor der anvendes humane levermikrosomer
Studies in humans and in vitro studies using human liver microsomes

Forsøg med mennesker og in vitro- forsøg, hvor der anvendes humane levermikrosomer
Studies in humans and in vitro studies using human liver microsomes

Andre lægemidlers potentielle indvirkning på INVEGA In vitro- forsøg indikerer, at CYP2D6 og CYP3A4 muligvis er minimalt involveret i metaboliseringen af paliperidon, men der er ingen indikationer, hverken in vitro eller in vivo, på, at disse isozymer spiller en signifikant rolle i metaboliseringen af paliperidon.
Potential for other medicines to affect INVEGA In vitro studies indicate that CYP2D6 and CYP3A4 may be minimally involved in paliperidone metabolism, but there are no indications in vitro nor in vivo that these isozymes play a significant role in the metabolism of paliperidone.

Yderligere in vitro- forsøg viste, at ambrisentan ikke hæmmer NTCP,
Additional in vitro studies showed that ambrisentan does not inhibit NTCP,

In vitro- forsøg har vist, at paliperidon er substrat for P- glycoprotein P- gp.
In vitro studies have shown that paliperidone is a P-glycoprotein(P-gp) substrate.

In vitro- forsøg tyder på, at omtrent 81% bindes til plasmaproteiner.
In vitro studies indicate that pemetrexed is approximately 81% bound to plasma proteins.