Examples of using Isoforms in English and their translations into Bulgarian
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Medicine
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Ecclesiastic
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Ecclesiastic
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Computer
the major cytochrome P450 isoforms.
CYP2D6) of several CYP isoforms.
Therefore FABLYN is unlikely to alter the pharmacokinetics of medicinal products that are cleared by metabolism via these CYP isoforms, or are transported by MDR1 P-glycoprotein.
Based on in vitro data, nelfinavir is unlikely to inhibit other cytochrome P450 isoforms at concentrations in the therapeutic range.
nelfinavir is unlikely to inhibit other cytochrome P450 isoforms at concentrations in the therapeutic range.
adefovir did not inhibit any of the following human CYP450 isoforms, CYP1A2, CYP2D6,
All three isoforms of the deiodinases are selenium-containing enzymes;
The major CYP450 isoforms responsible for the phase I metabolism of cannabidiol are CYP2C19 and CYP3A4.
OATP isoforms, MRP2 and breast cancer resistance protein(BCRP)
In vitro, talazoparib did not inhibit any of the major uridine-diphosphate glucuronosyltransferase(UGT) isoforms(1A1, 1A4,
Concurrent use of substances which are metabolised by CYP450 isoforms may result in higher
blocks both CGRP isoforms(α-and β-CGRP)
In vitro, levetiracetam and its primary metabolite have been shown not to inhibit the major human liver cytochrome P450 isoforms(CYP3A4, 2A6,
Interaction with substrates of CYP 450 isoforms are thus not expected and have not been shown.
It is unlikely that atosiban inhibits hepatic cytochrome P450 isoforms in humans(see section 4.5).
Sildenafil metabolism is principally mediated by the cytochrome P450(CYP) isoforms 3A4(major route)
no inhibition of CYP450 isoforms except for CYP2C19.
whereas several UGT isoforms(1A1, 1A3,
CYP isoforms 2E1, 1A2, 2B6, 2C8, and 2C19 are involved to a lesser extent and isoforms 2D6 and 2C9 are not involved in the metabolism of lomitapide.
This is predominantly via cytochrome P450 2C8 although other isoforms may be involved to a lesser degree.