MULTIPLE DOSING in Croatian translation

• višekratnog doziranja
• višestrukog doziranja
• višestrukih doza
• višekratne doze
• višestruko doziranje
• višekratne primjene

Examples of using Multiple dosing in English and their translations into Croatian

However, these differences between the two age groups diminished after multiple dosing on Day 8, and the steady state pre-dose plasma levels of Canrenone raw powder and‘total metabolites' were significantly higher in the elderly subjects.
Međutim, te razlike između dvije dobne skupine smanjile su se nakon višestrukog doziranja na Dan 8, a razine ravnoteže prije doziranja plazme kanrenonskih sirovog praha i"ukupnih metabolita" bile su znatno više u starijih ispitanika.

Following multiple dosing in patients, modified-release levodopa/carbidopa had reduced fluctuations in levodopa plasma concentrations with peak-to-trough fluctuation index of 1.5 with minimal accumulation of levodopa.
Nakon višestrukog doziranja u bolesnika, levodopa/karbidopa s prilagođenim oslobađanjem smanjila je fluktuacije u koncentraciji levodope u plazmi s indeksom fluktuacije od vršne do najniže vrijednosti koncentracije lijeka od 1, 5 s minimalnim nakupljanjem levodope.

The lack of effect of cinacalcet on the pharmacokinetics of R-and S-warfarin and the absence of auto- induction upon multiple dosing in patients indicates that cinacalcet is not an inducer of CYP3A4,
Neučinkovitost sinakalceta na farmakokinetikuR- i S-varfarina i izostanak autoindukcije nakon višestrukih doza, pokazuje da sinakalcet nije induktor CYP3A4,

Multiple dosing of 800/200 mg Kaletra once daily for 2 weeks without meal restriction(n=16) produced a mean±
Višekratne doze lijeka Kaletra 800/200 mg jednom dnevno kroz 2 tjedna bez ograničavanja jela(n=16)

Thus, steady state plasma concentrations of afatinib were achieved within 8 days of multiple dosing of afatinib resulting in an accumulation of 2.77-fold(AUC0-∞)
Stoga su koncentracije afatiniba u plazmi pri stanju dinamičke ravnoteže postignute u roku 8 dana od višestrukog doziranja afatiniba, što je rezultiralo akumulacijom 2,

to 42- 64 ml/kg after multiple dosing(48-192 IU/kg), respectively.
odnosno 42-64 ml/kg nakon višestrukih doza 48-192 IU/kg.

Multiple dosing of perampanel 12 mg/day increased levels of anger,
Višekratne doze perampanela od 12 mg na dan povisile su razine ljutnje,

to approximately 25-30 hours following multiple dosing with 200-400 mg/day.
oko 45 sati(jednokratna doza) na oko 25-30 sati nakon višestrukog doziranja 200-400 mg/dan.

accumulate more upon multiple dosing than does AsIII.
zbog njihova duljeg poluvremena, akumuliraju se više nakon višestrukog doziranja nego AsIII.

slightly exceeding the exposure in humans after multiple dosing of 500 mg.
nešto veće u odnosu na izloženost u ljudi nakon višekratnih doza od 500 mg.

After multiple dosing of ritonavir to healthy volunteers(500 mg twice daily)
Nakon višekratnog doziranja ritonavira zdravim dobrovoljcima(500 mg dva puta na dan)

In vitro studies showed that rasagiline at a concentration of 1 µg/ml(equivalent to a level that is 160 times the average Cmax~ 5.9-8.5 ng/ml in Parkinson's disease patients after 1 mg rasagiline multiple dosing), did not inhibit cytochrome P450 isoenzymes, CYP1A2, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4 and CYP4A.
Ispitivanja in vitro su pokazala da razagilin u koncentraciji od 1 µg/ml(istovjetno razini koja je 160 puta veća od prosječne Cmax~ 5, 9-8, 5 ng/ml u bolesnika s Parkinsonovom bolešću nakon višekratnog doziranja 1 mg razagilina) nije inhibirao izoenzime citokroma P450, CYP1A2, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2El, CYP3A4 i CYP4A.

Following multiple dosing of PegIntron(1.0 microgram/kg subcutaneously administered every week for four weeks)
Nakon primjene višekratnih doza lijeka PegIntron(1, 0 mikrograma/kg supkutano, svakog tjedna tijekom četiri tjedna)

Table A: Pharmacokinetic Parameters at Multiple Dose Levels after a Single Infusion of Oxyglobin.
Tablica A: Farmakokinetički parametri pri razinama višestrukih doza nakon jedne infuzije proizvoda Oxyglobin.

Multiple dose 20 mg/day.
Višestruke doze 20 mg na dan.

The clinical relevance of this finding to multiple dose administration is not clear.
Klinički značaj ovog nalaza za višestruke doze nije jasan.

The clinical relevance of this finding to multiple dose administration is not clear.
Kliničko značenje tog nalaza u uvjetima višekratnog doziranja nije jasno.

Digoxin(0.5 mg single dose)/Cobicistat 150 mg multiple doses.
Digoksin(jedna doza od 0, 5 mg)/ kobicistat više doza od 150 mg.

Dose proportionality was demonstrated in the single and multiple dose studies.
Proporcionalnost doze dokazana je u ispitivanjima s jednokratnim i višekratnim dozama.

Each pen contains multiple doses.
Jedna brizgalica sadrži više doza lijeka.