Examples of using A substrate in English and their translations into Finnish
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Medicine
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Colloquial
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Official
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Financial
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Ecclesiastic
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Official/political
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Computer
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Programming
is a substrate, a moderate inhibitor, and an inducer of CYP3A4.
Tipranavir is a substrate, an inducer and an inhibitor of cytochrome P450 CYP3A.
Under this name, understand cultivation of plantswithout using a substrate.
In vitro, lenalidomide is a substrate of P-gp, but is not a P-gp inhibitor.
Eltrombopag is a substrate for BCRP, but is not a substrate for P-glycoprotein or OATP1B1.
Avanafil is a substrate of and predominantly metabolised by CYP3A4.
Trifluridine is a substrate of TPase, but is not metabolised by cytochrome P450 CYP.
Aprepitant is a substrate and a dose-dependent inhibitor of CYP3A4.
Elimination Simvastatin is a substrate of CYP3A4 see sections 4.3 and 4.5.
Lenvatinib is a substrate for P-gp and BCRP.
Isavuconazole is a substrate of CYP3A4 and CYP3A5 see section 5.2.
Its active metabolite is a substrate for OATP1B1.
Lesinurad is a substrate of OATP1B1, OAT1, OAT3 and OCT1.
The active metabolite of irinotecan, SN-38, is a substrate for OATP1B1 and UGT1A1.
Metabolite NW-1153 is not a substrate for OCT2, or OAT1, but it is substrate for OAT3.
Dabrafenib is a substrate of human P-glycoprotein(Pgp) and murine BCRP in vitro.
Piperaquine is also a substrate of CYP3A4.
Grazoprevir is a substrate of OATP1B drug transporters.
In vitro studies have shown that degarelix is not a substrate for the human CYP450 system.
This type is equipped with a substrate, well it holds a temporary static load,