Duration of response obtained with alectinib also exceeded the corresponding results observed with crizotinib in patients with and without prior radiation.
明らかに、C型肝炎の感染は、患者のがん治療の奏効に影響する可能性があります。
Obviously, a hepatitis C infection could impact how patients respond to their cancer therapy.
The overall objective response rate was 20.5% for patients who were randomly assigned to treatment with topotecan and 13.2% for patients who were randomly assigned to treatment with paclitaxel(P= .138).
A targeted therapy resurrected by the Moon Shots Program at The University of Texas MD Anderson Cancer Center has produced unprecedented response rates among patients with metastatic non-small cell lung cancer that carries a highly treatment-resistant mutation.
In a previous trial, similar patients treated with a combination of trastuzumab, capecitabine, and cisplatin(but not bevacizumab) had an overall survival of 13.8 months and a 47% response rate.
Responses of 20% to 56% have been reported for lenalidomide, especially in patients with follicular lymphoma and small lymphocytic lymphoma, with even higher responses noted for the combination of lenalidomide and rituximab.
Objective response rates did not differ significantly between the two arms(80% vs. 76%; p 0.2335), but osimertinib gave rise to a doubling of the duration of response 17.2 vs. 8.5 months.
The systemic chemotherapy resulted in one complete response and three partial responses in a total of five patients, suggesting that this therapy may be an option for treatment of extensive lesions.
Ten of these(22%) achieved major pathological responses, which were defined as≤ 10% viable tumour cells. Three patients(7%) had pathological complete remissions.
A small retrospective study of nine adult patients with metastatic alveolar soft part sarcoma treated with sunitinib reported partial responses in five patients and stable disease in two patients.
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