Eksempler på brug af Protein binding på Engelsk og deres oversættelser til Dansk
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In humans, the protein binding of pramipexole is very low(< 20%) and the volume of distribution is large 400 l.
Protein binding is slight(binding of perindoprilat to angiotensin converting enzyme is less than 30%), but is concentration-dependent.
In vitro protein binding of tenofovir to plasma
TMZ demonstrates low protein binding(10% to 20%), and thus it is not expected to interact with highly protein-bound substances.
Distribution Plasma protein binding of the active metabolite is low with approximately 50% bound to albumin and alpha-1-acid glycoprotein.
Plasma pharmacokinetics and protein binding of gadofosveset were not significantly influenced by moderate hepatic impairment Child Pugh B.
Plasma protein binding of rosiglitazone is high(approximately 99.8%) and is not influenced by concentration or age.
Concurrent use of other substances with a high degree of protein binding may compete with masitinib binding
Concurrent use of other active substances that have a high degree of protein binding may compete with robenacoxib for binding
substances with high protein binding may compete for binding
When activity, concentrations and protein binding are taken into account,
No difference was observed in the extent of lumiracoxib protein binding in synovial fluid compared to plasma.
substances with high protein binding may compete for binding
substances with high protein binding may compete for binding
Plasma protein binding of lumiracoxib was similar in healthy subjects and in patients with end-stage renal disease.
Low protein binding filters for sterile filtration of biological samples, serum and cell culture media.
Distribution The serum protein binding of ramipril is about 73% and that of ramiprilat about 56.
Therefore, a 0.2 micron low protein binding in-line filter should be used for administration.
interactions involving plasma protein binding are not expected to have any clinically relevant effects on lumiracoxib or co-administered drugs.
In vitro studies have demonstrated a very low potential for interaction with other medicinal products and protein binding interactions see section 5.2.